(Q45831582)

16 December 2017

review article

1 reference

title

Parallel progression of primary tumours and metastases (English)

1 reference

16 December 2017

author name string

Christoph A Klein

series ordinal

1 reference

16 December 2017

language of work or name

English

0 references

publication date

1 April 2009

1 reference

16 December 2017

published in

Nature Reviews Cancer

1 reference

16 December 2017

volume

1 reference

16 December 2017

issue

1 reference

16 December 2017

page(s)

302-312

1 reference

16 December 2017

cites work

Cancer statistics, 2008

1 reference

Tyrosine kinase inhibitors: why does the current process of clinical development not apply to them?

31 March 2020

1 reference

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

31 March 2020

1 reference

Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

31 March 2020

1 reference

Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy

31 March 2020

1 reference

A genetic model for colorectal tumorigenesis

31 March 2020

1 reference

Mutation selection and the natural history of cancer

31 March 2020

1 reference

The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

31 March 2020

1 reference

Do generalized metastases occur directly from the primary?

31 March 2020

1 reference

Mechanisms of malignant progression

31 March 2020

1 reference

On the growth rates of human malignant tumors: Implications for medical decision making

31 March 2020

1 reference

The staging of cancer: a retrospective and prospective appraisal

31 March 2020

1 reference

The lethal phenotype of cancer: the molecular basis of death due to malignancy

31 March 2020

1 reference

Rates of growth of human neoplasms: Part II.

31 March 2020

1 reference

RATES OF GROWTH OF PULMONARY METASTASES AND HOST SURVIVAL

31 March 2020

1 reference

The gross rates of growth of human mammary carcinoma

31 March 2020

1 reference

Growth rate of hepatic metastases in colorectal carcinoma

31 March 2020

1 reference

Age-dependent growth rate of primary breast cancer

31 March 2020

1 reference

The process of metastasisation for breast cancer

31 March 2020

1 reference

[Colorectal cancer metastasis. Frequency, prognosis, and consequences]

31 March 2020

1 reference

Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients

31 March 2020

1 reference

Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992

31 March 2020

1 reference

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

31 March 2020

1 reference

Systemic endocrine instigation of indolent tumor growth requires osteopontin

31 March 2020

1 reference

Micrometastatic cancer cells in bone marrow: in vitro detection with anti-cytokeratin and in vivo labeling with anti-17-1A monoclonal antibodies

31 March 2020

1 reference

The systemic progression of human cancer: a focus on the individual disseminated cancer cell--the unit of selection

31 March 2020

1 reference

Detection and clinical importance of micrometastatic disease

31 March 2020

1 reference

A concept for the standardized detection of disseminated tumor cells in bone marrow from patients with primary breast cancer and its clinical implementation

31 March 2020

1 reference

Review: Biological relevance of disseminated tumor cells in cancer patients

31 March 2020

1 reference

Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells

31 March 2020

1 reference

Combined transcriptome and genome analysis of single micrometastatic cells

31 March 2020

1 reference

Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer

31 March 2020

1 reference

From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression

31 March 2020

1 reference

Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer.

31 March 2020

1 reference

Perioperative activation of disseminated tumor cells in bone marrow of patients with prostate cancer

31 March 2020

1 reference

Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer.

31 March 2020

1 reference

Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of Ki-ras and p53 mutations.

31 March 2020

1 reference

Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer

31 March 2020

1 reference

Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver

31 March 2020

1 reference

Phenotype of bone metastases of non-small cell lung cancer: epidermal growth factor receptor expression and K-RAS mutational status

31 March 2020

1 reference

Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC.

31 March 2020

1 reference

Comparison of epidermal growth factor receptor mutations between primary and corresponding metastatic tumors in tyrosine kinase inhibitor-naive non-small-cell lung cancer

31 March 2020

1 reference

The genomic heritage of lymph node metastases: implications for clinical management of patients with breast cancer

31 March 2020

1 reference

Evaluation of the clonal relationship between primary and metastatic renal cell carcinoma by comparative genomic hybridization

31 March 2020

1 reference

Genetically heterogeneous and clonally unrelated metastases may arise in patients with cutaneous melanoma

31 March 2020

1 reference

Comparative lesion sequencing provides insights into tumor evolution

31 March 2020

1 reference

Gene expression profiles of primary breast tumors maintained in distant metastases

31 March 2020

1 reference

Host genetics influence tumour metastasis

31 March 2020

1 reference

Systemic spread is an early step in breast cancer

31 March 2020

1 reference

Class I PI3K in oncogenic cellular transformation.

31 March 2020

1 reference

Genomic imbalances in 5918 malignant epithelial tumors: an explorative meta-analysis of chromosomal CGH data

31 March 2020

1 reference

Haematogenous metastatic patterns in colonic carcinoma: an analysis of 1541 necropsies

31 March 2020

1 reference

Metastatic patterns of renal carcinoma: an analysis of 687 necropsies

31 March 2020

1 reference

Systemic cancer progression and tumor dormancy: mathematical models meet single cell genomics

31 March 2020

1 reference

I. The Results of Radical Operations for the Cure of Carcinoma of the Breast

31 March 2020

1 reference

Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation.

31 March 2020

1 reference

Randomized trial comparing axillary clearance versus no axillary clearance in older patients with breast cancer: first results of International Breast Cancer Study Group Trial 10-93.

31 March 2020

1 reference

The dissection of internal mammary nodes does not improve the survival of breast cancer patients. 30-year results of a randomised trial

31 March 2020

1 reference

Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier

31 March 2020

1 reference

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

31 March 2020

1 reference

Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer

31 March 2020

1 reference

Brain metastases: the HER2 paradigm

31 March 2020

1 reference

Immunomagnetic enrichment, genomic characterization, and prognostic impact of circulating melanoma cells.

31 March 2020

1 reference

Circulating tumor cells, disease progression, and survival in metastatic breast cancer

31 March 2020

1 reference

Circulating tumor cells in metastatic breast cancer: from prognostic stratification to modification of the staging system?

31 March 2020

1 reference

Detection of mutations in EGFR in circulating lung-cancer cells

31 March 2020

1 reference

Adaptation versus selection: the origins of metastatic behavior

31 March 2020

1 reference

A multigenic program mediating breast cancer metastasis to bone

31 March 2020

1 reference

Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression

31 March 2020

1 reference

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

31 March 2020

1 reference

Efficient tumour formation by single human melanoma cells

31 March 2020

1 reference

High resolution array-CGH analysis of single cells

31 March 2020

1 reference

High-resolution array comparative genomic hybridization of single micrometastatic tumor cells.

31 March 2020

1 reference

The direct molecular analysis of metastatic precursor cells in breast cancer: a chance for a better understanding of metastasis and for personalised medicine

31 March 2020

1 reference

Dissecting the metastatic cascade

31 March 2020

1 reference

Detection, clinical relevance and specific biological properties of disseminating tumour cells

31 March 2020

1 reference

Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors

31 March 2020

1 reference

Predicting the course of Gompertzian growth

31 March 2020

1 reference

Proliferation index in various stages of breast cancer determined by Ki-67 immunostaining

31 March 2020

1 reference

Carcinoma of the colon and rectum--growth rate

31 March 2020

1 reference

Observations on the doubling time of prostate cancer.The use of serial prostate-specific antigen in patients with untreated disease as a measure of increasing cancer volume

31 March 2020

1 reference

Metastatic prostate carcinoma to bone: clinical and pathologic features associated with cancer-specific survival

31 March 2020

1 reference

Haematogenous dissemination of cells from human renal adenocarcinomas

31 March 2020

1 reference

31 March 2020

The dormant cancer cell

1 reference

Differential Expression of Proliferation-Associated Molecules in Individual Micrometastatic Carcinoma Cells

31 March 2020

1 reference

Genes that mediate breast cancer metastasis to lung

31 March 2020

1 reference

Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes.

31 March 2020

1 reference

Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study

31 March 2020

1 reference

12 December 2020

Mechanisms of human tumor metastasis studied in patients with peritoneovenous shunts

1 reference

12 December 2020

Cell proliferation in prostate cancer patients with lymph node metastasis: a marker for progression

1 reference

12 December 2020

The many faces of tumor dormancy

1 reference

12 December 2020

An autopsy study of metastatic sites of breast cancer

1 reference

12 December 2020

Foulds' Dangerous Idea Revisited: The Multistep Development of Tumors 40 Years Later

1 reference

12 December 2020

Selection of Successive Tumour Lines for Metastasis

1 reference

12 December 2020

Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer.

1 reference

12 December 2020

Observations on growth rates of human tumors

1 reference

12 December 2020

Serum concentrations of hepatocyte growth factor in breast cancer patients

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC2627

1 reference

16 December 2017

Dimensions Publication ID

1052526028

0 references

1 reference

16 December 2017