(Q45872960)

17 December 2017

title

Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state (English)

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17 December 2017

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17 December 2017

Alessio Cantore

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17 December 2017

Mario Amendola

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Luigi Naldini

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17 December 2017

Giovanna Lazzari

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17 December 2017

Silvia Colleoni

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Silvia Colleoni

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17 December 2017

author name string

Brian D Brown

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17 December 2017

Anna Zingale

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17 December 2017

Alessia Baccarini

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17 December 2017

Cesare Galli

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17 December 2017

publication date

16 November 2007

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17 December 2017

published in

Nature Biotechnology

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17 December 2017

volume

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17 December 2017

issue

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17 December 2017

page(s)

1457-1467

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17 December 2017

The leading edge of stem cell therapeutics

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Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors

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Dangerous liaisons: the role of "danger" signals in the immune response to gene therapy

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Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice

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Adeno-associated virus vector-mediated gene transfer into dystrophin-deficient skeletal muscles evokes enhanced immune response against the transgene product

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Transcriptionally targeted adenovirus vectors

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Engineering targeted viral vectors for gene therapy

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Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells

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microRNAs: tiny regulators with great potential

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7 January 2021

MicroRNAs: genomics, biogenesis, mechanism, and function

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Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

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7 January 2021

Identification of tissue-specific microRNAs from mouse

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7 January 2021

A mammalian microRNA expression atlas based on small RNA library sequencing

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7 January 2021

Micro RNAs in animal development.

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7 January 2021

Common logic of transcription factor and microRNA action

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7 January 2021

MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb

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7 January 2021

Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer

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7 January 2021

MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression

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7 January 2021

A functional study of miR-124 in the developing neural tube

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7 January 2021

Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions

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Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters.

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7 January 2021

Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans

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7 January 2021

Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.

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Relief of microRNA-mediated translational repression in human cells subjected to stress

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microRNAs: a safeguard against turmoil?

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A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

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7 January 2021

miR-15 and miR-16 induce apoptosis by targeting BCL2

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7 January 2021

siRNAs can function as miRNAs

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7 January 2021

Dendritic cells as therapeutic vaccines against cancer

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7 January 2021

Tolerogenic dendritic cells

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7 January 2021

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

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7 January 2021

MicroRNA-155 is induced during the macrophage inflammatory response

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7 January 2021

MicroRNAs modulate hematopoietic lineage differentiation

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7 January 2021

An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling.

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7 January 2021

Human embryonic stem cells express a unique set of microRNAs

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7 January 2021

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

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7 January 2021

Competition for RISC binding predicts in vitro potency of siRNA.

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7 January 2021

The evolution of gene regulation by transcription factors and microRNAs

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7 January 2021

A microRNA in a multiple-turnover RNAi enzyme complex

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Argonaute2 is the catalytic engine of mammalian RNAi

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Kinetic analysis of the RNAi enzyme complex

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miR-181a is an intrinsic modulator of T cell sensitivity and selection

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7 January 2021

The regulation of genes and genomes by small RNAs.

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7 January 2021

Sorting of Drosophila small silencing RNAs

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7 January 2021

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Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

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Long-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells

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7 January 2021

Principles of microRNA-target recognition

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7 January 2021

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

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7 January 2021

Dynamic regulation of miRNA expression in ordered stages of cellular development.

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7 January 2021

Real-time quantification of microRNAs by stem-loop RT-PCR

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7 January 2021

Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells

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7 January 2021

Identifiers

DOI

10.1038/NBT1372

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17 December 2017

Dimensions Publication ID

1005174220

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17 December 2017