(Q45866945)

English

Transfer of the CFTR Gene to the Lung of Nonhuman Primates with E1-Deleted, E2a-Defective Recombinant Adenoviruses: A Preclinical Toxicology Study

scientific article published on July 1, 1995

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/7578403

Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: a preclinical toxicology study (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/7578403

Transfer of the CFTR Gene to the Lung of Nonhuman Primates with E1-Deleted, E2a-Defective Recombinant Adenoviruses: A Preclinical Toxicology Study (English)

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

John F Engelhardt

3

object named as

J. F. Engelhardt

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7578403

20 May 2024

4

object named as

J. M. Wilson

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7578403

20 May 2024

author name string

M. J. Goldman

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7578403

20 May 2024

L. A. Litzky

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7578403

20 May 2024

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publication date

1 July 1995

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/7578403

full work available at URL

http://www.liebertpub.com/doi/pdf/10.1089/hum.1995.6.7-839

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Human Gene Therapy

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/7578403

6

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/7578403

7

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/7578403

839-851

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/7578403

Acute responses of non-human primates to airway delivery of an adenovirus vector containing the human cystic fibrosis transmembrane conductance regulator cDNA.

1

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Submucosal glands are the predominant site of CFTR expression in the human bronchus

2

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study

3

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenoviruses.

4

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Prolonged transgene expression in cotton rat lung with recombinant adenoviruses defective in E2a.

5

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver

6

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Gene therapy in a xenograft model of cystic fibrosis lung corrects chloride transport more effectively than the sodium defect.

7

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

8

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Temperature-sensitive replication of H5ts125 adenovirus DNA in vitro

9

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo

10

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Gene transfer to freshly isolated human respiratory epithelial cells in vitro using a replication-deficient adenovirus containing the human cystic fibrosis transmembrane conductance regulator cDNA.

11

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study

12

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Cystic fibrosis

13

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Cystic fibrosis transmembrane conductance regulator: a chloride channel with novel regulation

14

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Federal Register

15

58

47906

author name string

WILSON J.M.

publication date

1992

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

17

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses.

18

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

19

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.

20

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats.

21

1 reference

10.1089/HUM.1995.6.7-839

https://api.crossref.org/works/10.1089/HUM.1995.6.7-839

20 May 2024

Identifiers

10.1089/HUM.1995.6.7-839

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/7578403

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/7578403

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