(Q45857246)

17 December 2017

title

Intratumoural interleukin 12 gene therapy stimulates the immune system and decreases angiogenesis in dogs with spontaneous cancer (English)

1 reference

17 December 2017

author name string

L Cicchelero

1 reference

17 December 2017

S Denies

1 reference

17 December 2017

H Haers

1 reference

17 December 2017

K Vanderperren

1 reference

17 December 2017

E Stock

1 reference

17 December 2017

L Van Brantegem

1 reference

17 December 2017

H de Rooster

1 reference

17 December 2017

N N Sanders

1 reference

17 December 2017

publication date

9 August 2016

1 reference

17 December 2017

Veterinary and Comparative Oncology

published in

1 reference

17 December 2017

volume

1 reference

17 December 2017

issue

1 reference

17 December 2017

page(s)

1187-1205

1 reference

17 December 2017

The tumor-draining lymph node as an immune-privileged site

cites work

1 reference

New insights into IL-12-mediated tumor suppression.

21 January 2018

1 reference

The role of interleukin-12 on modulating myeloid-derived suppressor cells, increasing overall survival and reducing metastasis

21 January 2018

1 reference

Interleukin 12 stimulates IFN-gamma-mediated inhibition of tumor-induced regulatory T-cell proliferation and enhances tumor clearance

21 January 2018

1 reference

IL-12 inhibits the TGF-β-dependent T cell developmental programs and skews the TGF-β-induced differentiation into a Th1-like direction.

21 January 2018

1 reference

Interleukin-12: biological properties and clinical application

21 January 2018

1 reference

IL-12 regulates VEGF and MMPs in a murine breast cancer model

21 January 2018

1 reference

The toxicology of interleukin-12: a review

21 January 2018

1 reference

Cancer electrogene therapy with interleukin-12.

21 January 2018

1 reference

Intracellular tracking of single-plasmid DNA particles after delivery by electroporation

21 January 2018

1 reference

Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases

21 January 2018

1 reference

Intratumoral bleomycin and IL-12 electrochemogenetherapy for treating head and neck tumors in dogs.

21 January 2018

1 reference

IL-12 based gene therapy in veterinary medicine

21 January 2018

1 reference

Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma

21 January 2018

1 reference

Bleomycin/interleukin-12 electrochemogenetherapy for treating naturally occurring spontaneous neoplasms in dogs

21 January 2018

1 reference

Electrogene therapy with interleukin-12 in canine mast cell tumors

21 January 2018

1 reference

Safety and efficacy of tumor-targeted interleukin 12 gene therapy in treated and non-treated, metastatic lesions

21 January 2018

1 reference

Electroporation-mediated IL-12 gene therapy in a transplantable canine cancer model

21 January 2018

1 reference

Detection, cDNA cloning and sequencing of canine interleukin 12.

21 January 2018

1 reference

Validation of dynamic contrast-enhanced ultrasound in predicting outcomes of antiangiogenic therapy for solid tumors: the French multicenter support for innovative and expensive techniques study

21 January 2018

1 reference

The effect of anesthesia with propofol and sedation with butorphanol on quantitative contrast-enhanced ultrasonography of the healthy feline kidney.

21 January 2018

1 reference

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 January 2018

1 reference

Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells

21 January 2018

1 reference

IL-12 plasmid delivery by in vivo electroporation for the successful treatment of established subcutaneous B16.F10 melanoma

21 January 2018

1 reference

Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning

21 January 2018

1 reference

Administration route- and immune cell activation-dependent tumor eradication by IL12 electrotransfer

21 January 2018

1 reference

Reversing tumor immune suppression with intratumoral IL-12: activation of tumor-associated T effector/memory cells, induction of T suppressor apoptosis, and infiltration of CD8+ T effectors.

21 January 2018

1 reference

Double-blind placebo-controlled study with interleukin-18 and interleukin-12-encoding plasmid DNA shows antitumor effect in metastatic melanoma in gray horses

21 January 2018

1 reference

Efficient electrotransfection into canine muscle

21 January 2018

1 reference

Electroporation mediated DNA vaccination directly to a mucosal surface results in improved immune responses

21 January 2018

1 reference

Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect

21 January 2018

1 reference

Functional expression of IL-12 receptor by human eosinophils: IL-12 promotes eosinophil apoptosis

21 January 2018

1 reference

Involvement of eosinophils in the anti-tumor response

21 January 2018

1 reference

Gamma interferon suppresses erythropoiesis via interleukin-15.

21 January 2018

1 reference

IL-24: a classic cytokine and/or a potential cure for cancer?

21 January 2018

1 reference

Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions?

21 January 2018

1 reference

Reducing tumor growth and angiogenesis using a triple therapy measured with Contrast-enhanced ultrasound (CEUS)

21 January 2018

1 reference

Regression of tumor growth and induction of long-term antitumor memory by interleukin 12 electro-gene therapy

21 January 2018

1 reference

In vivo electrogene transfer of interleukin-12 inhibits tumor growth and lymph node and lung metastases in mouse mammary carcinomas

21 January 2018

1 reference

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma

21 January 2018

1 reference

Clinical trials of immunogene therapy for spontaneous tumors in companion animals

21 January 2018

1 reference

Depression in cancer: new developments regarding diagnosis and treatment

21 January 2018

1 reference

Cytokine dysregulation, inflammation and well-being.

21 January 2018

1 reference

Combination of interleukin-12 gene therapy, metronomic cyclophosphamide and DNA cancer vaccination directs all arms of the immune system towards tumor eradication

21 January 2018

1 reference

Targeting inhibitory pathways in cancer immunotherapy

21 January 2018

1 reference

The etiology of paraneoplastic autoimmunity

21 January 2018

1 reference

Metabolic considerations in management of surgical patients

21 January 2018

1 reference

Introduction of genes via sonoporation and electroporation

21 January 2018

1 reference

Clinical and immunomodulatory effects of toceranib combined with low-dose cyclophosphamide in dogs with cancer

21 January 2018

1 reference

Central role of IFNgamma-indoleamine 2,3-dioxygenase axis in regulation of interleukin-12-mediated antitumor immunity

21 January 2018

1 reference

Cytokine-Enhanced Vaccine and Interferon-β plus Suicide Gene Therapy as Surgery Adjuvant Treatments for Spontaneous Canine Melanoma

21 January 2018

1 reference

Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer

21 January 2018

1 reference

The promising alliance of anti-cancer electrochemotherapy with immunotherapy

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/VCO.12255

1 reference

17 December 2017

1 reference

17 December 2017