(Q45530812)

14 December 2017

title

Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene (English)

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respiratory syncytial virus

14 December 2017

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Weidong Zhang

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14 December 2017

Hong Yang

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14 December 2017

Xiaoyuan Kong

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14 December 2017

Subhra Mohapatra

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14 December 2017

Homero San Juan-Vergara

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14 December 2017

Gary Hellermann

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14 December 2017

Sumita Behera

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14 December 2017

Rajeswari Singam

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14 December 2017

Richard F Lockey

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14 December 2017

Shyam S Mohapatra

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14 December 2017

language of work or name

English

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publication date

26 December 2004

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14 December 2017

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14 December 2017

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14 December 2017

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14 December 2017

page(s)

56-62

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Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7.

14 December 2017

cites work

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Bronchiolitis-associated hospitalizations among US children, 1980-1996.

21 January 2018

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Respiratory syncytial virus infections in previously healthy working adults

21 January 2018

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Mortality associated with influenza and respiratory syncytial virus in the United States

21 January 2018

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Pathogenesis of RSV lower respiratory tract infection: implications for vaccine development

21 January 2018

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Basic epidemiology and immunopathology of RSV in children.

21 January 2018

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Recombinant respiratory syncytial viruses with deletions in the NS1, NS2, SH, and M2-2 genes are attenuated in vitro and in vivo

21 January 2018

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Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees

21 January 2018

1 reference

Immunity to and frequency of reinfection with respiratory syncytial virus

21 January 2018

1 reference

Respiratory Syncytial Virus Infection in Infants Is Associated with Predominant Th-2-like Response

21 January 2018

1 reference

Recurrent respiratory syncytial virus infections in allergen-sensitized mice lead to persistent airway inflammation and hyperresponsiveness

21 January 2018

1 reference

Adenovirus-mediated interferon gamma gene therapy for allergic asthma: involvement of interleukin 12 and STAT4 signaling

21 January 2018

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Intranasal IFN-gamma gene transfer protects BALB/c mice against respiratory syncytial virus infection

21 January 2018

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Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection

21 January 2018

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Mucosal gene expression vaccine: a novel vaccine strategy for respiratory syncytial virus

21 January 2018

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Respiratory syncytial virus (RSV) nonstructural (NS) proteins as host range determinants: a chimeric bovine RSV with NS genes from human RSV is attenuated in interferon-competent bovine cells

21 January 2018

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Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3

21 January 2018

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Bovine respiratory syncytial virus nonstructural proteins NS1 and NS2 cooperatively antagonize alpha/beta interferon-induced antiviral response

21 January 2018

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Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]

21 January 2018

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RNA-triggered gene silencing

21 January 2018

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Iduronic acid-containing glycosaminoglycans on target cells are required for efficient respiratory syncytial virus infection

21 January 2018

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Transcriptional and posttranscriptional regulation of exogenous human beta interferon gene in simian cells defective in interferon synthesis

21 January 2018

1 reference

Targeted therapy of respiratory syncytial virus in African green monkeys by intranasally administered 2-5A antisense

21 January 2018

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Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.

21 January 2018

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How cells respond to interferons

21 January 2018

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On the role of IRF in host defense

21 January 2018

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21 January 2018

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Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either

21 January 2018

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Activation of the interferon system by short-interfering RNAs

21 January 2018

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Determinants of interferon-stimulated gene induction by RNAi vectors

21 January 2018

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Monocyte interleukin-12 production is inversely related to duration of respiratory failure in respiratory syncytial virus bronchiolitis

21 January 2018

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Respiratory syncytial virus decreases the capacity of myeloid dendritic cells to induce interferon-gamma in naïve T cells

21 January 2018

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Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

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Childhood asthma following hospitalization with acute viral bronchiolitis in infancy

21 January 2018

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7 January 2021

Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection

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7 January 2021

Altered growth characteristics of recombinant respiratory syncytial viruses which do not produce NS2 protein

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7 January 2021

Chitosan IFN-gamma-pDNA Nanoparticle (CIN) Therapy for Allergic Asthma

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7 January 2021

Genetic therapy: on the brink of a new future

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7 January 2021

Attenuation of dengue virus infection by adeno-associated virus-mediated siRNA delivery

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7 January 2021

Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells

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7 January 2021

The NS1 protein of human respiratory syncytial virus is a potent inhibitor of minigenome transcription and RNA replication

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7 January 2021

Immunostimulatory DNA sequences necessary for effective intradermal gene immunization

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7 January 2021

Identifiers

DOI

10.1038/NM1174

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Dimensions Publication ID

14 December 2017

1042953105

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