(Q45302500)

English

Tissue-specific proteolysis of Huntingtin (htt) in human brain: evidence of enhanced levels of N- and C-terminal htt fragments in Huntington's disease striatum.

scientific article published in March 2001

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scholarly article

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Europe PubMed Central

PubMed publication ID

11 December 2017

Tissue-specific proteolysis of Huntingtin (htt) in human brain: evidence of enhanced levels of N- and C-terminal htt fragments in Huntington's disease striatum (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

Huntington's disease

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

L M Mende-Mueller

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

T Toneff

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

S R Hwang

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

M F Chesselet

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

V Y Hook

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

language of work or name

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publication date

1 March 2001

1 reference

Europe PubMed Central

PubMed publication ID

11 December 2017

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

21

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

1830-1837

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of normal and mutant huntingtin in the developing brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances on the pathogenesis of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntington's disease gene (IT15) is widely expressed in human and rat tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kunitz protease inhibitor form of the amyloid precursor protein (KPI/APP) inhibits the proneuropeptide processing enzyme prohormone thiol protease (PTP). Colocalization of KPI/APP and PTP in secretory vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homozygotes and heterozygotes for ciliary neurotrophic factor null alleles do not show earlier onset of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular studies define the primary structure of alpha1-antichymotrypsin (ACT) protease inhibitor in Alzheimer's disease brains. Comparison of act in hippocampus and liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning reveals isoforms of bovine alpha 1-antichymotrypsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for functional localization of the proenkephalin-processing enzyme, prohormone thiol protease, to secretory vesicles of chromaffin cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunochemical characterization of carboxypeptidase B-like peptide-hormone-processing enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic models of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntington disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.21-06-01830.2001

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762596&resulttype=core&format=json

12 May 2020

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