(Q44918715)

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Antidepressant-like effects of PDE4 inhibitors mediated by the high-affinity rolipram binding state (HARBS) of the phosphodiesterase-4 enzyme (PDE4) in rats

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Europe PubMed Central

PubMed publication ID

7 December 2017

Antidepressant-like effects of PDE4 inhibitors mediated by the high-affinity rolipram binding state (HARBS) of the phosphodiesterase-4 enzyme (PDE4) in rats (English)

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Europe PubMed Central

PubMed publication ID

7 December 2017

James M O'Donnell

8

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Europe PubMed Central

PubMed publication ID

7 December 2017

author name string

Han-Ting Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Yu Zhao

2

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Ying Huang

3

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Chengjun Deng

4

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Allen T Hopper

5

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Michael De Vivo

6

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Gregory M Rose

7

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Europe PubMed Central

PubMed publication ID

7 December 2017

publication date

4 April 2006

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Europe PubMed Central

PubMed publication ID

7 December 2017

Psychopharmacology

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Europe PubMed Central

PubMed publication ID

7 December 2017

186

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Europe PubMed Central

PubMed publication ID

7 December 2017

2

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Europe PubMed Central

PubMed publication ID

7 December 2017

209-217

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Europe PubMed Central

PubMed publication ID

7 December 2017

Antagonism of the antidepressant-like effects of clenbuterol by central administration of beta-adrenergic antagonists in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereospecific binding of the antidepressant rolipram to brain protein structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Effects in animal models of depression of lisuride alone and upon coadministration with antidepressants]

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Close correlation between behavioural response and binding in vivo for inhibitors of the rolipram-sensitive phosphodiesterase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of the inhibitory activity of PDE4 inhibitors on leukocyte PDE4 activity in vitro and eosinophil trafficking in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant-like effects of rolipram and other inhibitors of cyclic adenosine monophosphate phosphodiesterase on behavior maintained by differential reinforcement of low response rate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations of cAMP response element-binding activity in the aged rat brain in response to administration of rolipram, a cAMP-specific phosphodiesterase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biarylcarboxylic acids and -amides: inhibition of phosphodiesterase type IV versus [3H]rolipram binding activity and their relationship to emetic behavior in the ferret

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoradiographic mapping of a selective cyclic adenosine monophosphate phosphodiesterase in rat brain with the antidepressant [3H]rolipram

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the functional domains of human recombinant phosphodiesterase 4A: structural requirements for catalytic activity and rolipram binding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that cyclic AMP phosphodiesterase inhibitors suppress interleukin-2 release from murine splenocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant-induced increase in high-affinity rolipram binding sites in rat brain: dependence on noradrenergic and serotonergic function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rolipram forms a potent discriminative stimulus in drug discrimination experiments in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discriminative stimulus effects of the type-4 phosphodiesterase inhibitor rolipram in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The potential of phosphodiesterase 4 inhibitors for the treatment of depression: opportunities and challenges.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist interactions with beta adrenergic receptors in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proposal for Pharmacologically Distinct Conformers of PDE4 Cyclic AMP Phosphodiesterases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between the antidepressant-like behavioral effects of beta adrenergic agonists and the cyclic AMP PDE inhibitor rolipram in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitor binding to type 4 phosphodiesterase (PDE4) assessed using [3H]piclamilast and [3H]rolipram

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the effects of isoproterenol administered into the hippocampus, frontal cortex, or amygdala on behavior of rats maintained by differential reinforcement of low response rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective phosphodiesterase-4 inhibitors in chronic obstructive lung disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral effects of family-selective inhibitors of cyclic nucleotide phosphodiesterases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16586089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-006-0369-4

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

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