(Q44870037)

7 December 2017

title

Prepulse inhibition deficits in GAD65 knockout mice and the effect of antipsychotic treatment (English)

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7 December 2017

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7 December 2017

Scott A Heldt

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7 December 2017

Amanda Green

series ordinal

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7 December 2017

language of work or name

English

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publication date

1 September 2004

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7 December 2017

published in

Neuropsychopharmacology

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7 December 2017

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7 December 2017

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7 December 2017

page(s)

1610-1619

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Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

7 December 2017

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Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures

21 January 2018

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Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine

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Hyperactivity, decreased startle reactivity, and disrupted prepulse inhibition following disinhibition of the rat ventral hippocampus by the GABA(A) receptor antagonist picrotoxin

21 January 2018

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Selective deficits in prefrontal cortical GABAergic neurons in schizophrenia defined by the presence of calcium-binding proteins

21 January 2018

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Deficits in Small Interneurons in Prefrontal and Cingulate Cortices of Schizophrenic and Schizoaffective Patients

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Amygdalar activation alters the hippocampal GABA system: "partial" modelling for postmortem changes in schizophrenia

21 January 2018

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Startle reflex habituation in functional psychoses: a controlled study

21 January 2018

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Prestimulus effects on human startle reflex in normals and schizophrenics

21 January 2018

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Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies

21 January 2018

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Gating and habituation of the startle reflex in schizophrenic patients

21 January 2018

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Effect of antipsychotic treatment on the prepulse inhibition deficit of mGluR5 knockout mice

21 January 2018

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The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat.

21 January 2018

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Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat.

21 January 2018

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Long-term evaluation of isolation-rearing induced prepulse inhibition deficits in rats

21 January 2018

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Mesolimbic dopaminergic supersensitivity following electrical kindling of the amygdala

21 January 2018

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Reversal of startle gating deficits in transgenic mice overexpressing corticotropin-releasing factor by antipsychotic drugs

21 January 2018

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The effects of an early stressful life event on sensorimotor gating in adult rats.

21 January 2018

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Reversal of sensorimotor gating deficits in Brattleboro rats by acute administration of clozapine and a neurotensin agonist, but not haloperidol: a potential predictive model for novel antipsychotic effects

21 January 2018

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Developmental stress disrupts habituation but spares prepulse inhibition in young rats.

21 January 2018

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Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

21 January 2018

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Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study

21 January 2018

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Differential hippocampal expression of glutamic acid decarboxylase 65 and 67 messenger RNA in bipolar disorder and schizophrenia

21 January 2018

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A decrease of reelin expression as a putative vulnerability factor in schizophrenia

21 January 2018

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Cell-type specific alterations of cortical interneurons in schizophrenic patients

21 January 2018

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Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase

21 January 2018

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Deficient sensorimotor gating following seizures in amygdala-kindled rats

21 January 2018

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The acoustic startle response in rats--circuits mediating evocation, inhibition and potentiation

21 January 2018

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Sex differences in the acoustic startle response and prepulse inhibition in Wistar rats

21 January 2018

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Disruption of prepulse inhibition of startle reflex in a neurodevelopmental model of schizophrenia: reversal by clozapine, olanzapine and risperidone but not by haloperidol

21 January 2018

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Gene expression in dopamine and GABA systems in an animal model of schizophrenia: effects of antipsychotic drugs

21 January 2018

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To model a psychiatric disorder in animals: schizophrenia as a reality test

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Assessment of locomotor activity, acoustic and tactile startle, and prepulse inhibition of startle in inbred mouse strains and F1 hybrids: implications of genetic background for single gene and quantitative trait loci analyses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Deficits in prepulse inhibition and habituation in never-medicated, first-episode schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

"Early" and "late" effects of sustained haloperidol on apomorphine- and phencyclidine-induced sensorimotor gating deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Long-term social isolation enhances picrotoxin seizure susceptibility in mice: up-regulatory role of endogenous brain allopregnanolone in GABAergic systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Intra-accumbens infusions of antisense oligodeoxynucleotides to one isoform of glutamic acid decarboxylase mRNA, GAD65, but not to GAD67 mRNA, impairs sustained attention performance in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Flumazenil reverses the decrease in the hypnotic activity of pentobarbital by social isolation stress: are endogenous benzodiazepine receptor ligands involved?

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Inbred strain differences in prepulse inhibition of the mouse startle response

21 January 2018

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Amygdalar control of the mesocorticolimbic dopamine system: parallel pathways to motivated behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Dopamine D1 rather than D2 receptor agonists disrupt prepulse inhibition of startle in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

The novel atypical antipsychotic olanzapine, but not the CCK-B antagonist LY288513, blocks apomorphine-induced disruption of pre-pulse inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Apomorphine-induced disruption of prepulse inhibition that can be normalised by systemic haloperidol is insensitive to clozapine pretreatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Regional distribution and relative amounts of glutamate decarboxylase isoforms in rat and mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Two isoforms of glutamate decarboxylase: why?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Postnatal development of a GABA deficit and disturbance of neural functions in mice lacking GAD65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Altered conditioned fear behavior in glutamate decarboxylase 65 null mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Sensitivity to sensorimotor gating-disruptive effects of apomorphine in two outbred parental rat strains and their F1 and N2 progeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Distribution of glutamate decarboxylase65 immunoreactive puncta on pyramidal and nonpyramidal neurons in hippocampus of schizophrenic brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Impaired prefrontal inhibition in schizophrenia: relevance for cognitive dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Do D1/D2 interactions regulate prepulse inhibition in rats?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Reduced startle habituation and prepulse inhibition in mice lacking the adenosine A2A receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Synaptic plasticity in the acoustic startle pathway: the neuronal basis for short-term habituation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Implications of normal brain development for the pathogenesis of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Acoustic startle and prepulse inhibition in 40 inbred strains of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Involvement of serotonin 2A receptors in phencyclidine-induced disruption of prepulse inhibition of the acoustic startle in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Neurochemical changes in the entopeduncular nucleus and increased oral behavior in rats treated subchronically with clozapine or haloperidol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Effects of clozapine on behavioral and metabolic traits relevant for schizophrenia in two mouse strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Disruption of prepulse inhibition following N-methyl-D-aspartate infusion into the ventral hippocampus is antagonized by clozapine but not by haloperidol: a possible model for the screening of atypical antipsychotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

Absence of long-term depression in the visual cortex of glutamic Acid decarboxylase-65 knock-out mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

7 January 2021

The importance of acclimation in acoustic startle amplitude and pre-pulse inhibition testing of male and female rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

7 January 2021

Epigenetic sources of behavioral differences in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

7 January 2021

Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

7 January 2021

Short-term and long-term habituation of the acoustic startle response in chronic decerebrate rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

7 January 2021

Regulation of synaptic plasticity genes during consolidation of fear conditioning

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

7 January 2021

Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

7 January 2021

The pharmacology of mesolimbic dopamine neurons: a dual-probe microdialysis study in the ventral tegmental area and nucleus accumbens of the rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300468

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1300468

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Dimensions Publication ID

7 December 2017

1045476952

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