(Q44789930)

6 December 2017

title

Use of red-shifted dyes in a fluorescence polarization AKT kinase assay for detection of biological activity in natural product extracts (English)

1 reference

6 December 2017

1 reference

Tammy C Turek-Etienne

1 reference

6 December 2017

Ming Lei

1 reference

6 December 2017

Joseph S Terracciano

1 reference

6 December 2017

Erik F Langsdorf

1 reference

6 December 2017

Robert W Bryant

1 reference

6 December 2017

Richard F Hart

1 reference

6 December 2017

Ann C Horan

1 reference

6 December 2017

publication date

1 February 2004

1 reference

Journal of Biomolecular Screening

6 December 2017

published in

1 reference

6 December 2017

1 reference

6 December 2017

1 reference

6 December 2017

page(s)

52-61

1 reference

Tyrosine kinase inhibitors: from rational design to clinical trials

6 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

PKB binding proteins. Getting in on the Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Natural products in drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Pure compound libraries; a new perspective for natural product based drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

High-throughput method for the production and analysis of large natural product libraries for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Strategies for discovering drugs from previously unexplored natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Development and validation of a competitive AKT serine/threonine kinase fluorescence polarization assay using a product-specific anti-phospho-serine antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Evaluation of fluorescent compound interference in 4 fluorescence polarization assays: 2 kinases, 1 protease, and 1 phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

A scintillation proximity assay for the Raf/MEK/ERK kinase cascade: high-throughput screening and identification of selective enzyme inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Homogeneous proximity tyrosine kinase assays: scintillation proximity assay versus homogeneous time-resolved fluorescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

A cGMP-dependent protein kinase assay for high throughput screening based on time-resolved fluorescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Expression, purification, characterization and homology modeling of active Akt/PKB, a key enzyme involved in cell survival signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Imatinib mesylate (Gleevec, Glivec): a new therapy for chronic myeloid leukemia and other malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Recent natural products based drug development: a pharmaceutical industry perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Natural products in cancer chemotherapy: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Statistical Investigation into the Structural Complementarity of Natural Products and Synthetic Compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

A Homogeneous, Fluorescence Polarization Assay for Src-Family Tyrosine Kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

A Fluorescence Polarization Competition Immunoassay for Tyrosine Kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Identification of a high-affinity anti-phosphoserine antibody for the development of a homogeneous fluorescence polarization assay of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Development of high throughput screening assays using fluorescence polarization: nuclear receptor-ligand-binding and kinase/phosphatase assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

Development of a homogeneous time-resolved fluorescence assay for high throughput screening to identify Lck inhibitors: comparison with scintillation proximity assay and streptavidin-coated plate assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

FlashPlate scintillation proximity assays for characterization and screening of DNA polymerase, primase, and helicase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

AT2433-A1, AT2433-A2, AT2433-B1, and AT2433-B2 novel antitumor antibiotic compounds produced by Actinomadura melliaura. Taxonomy, fermentation, isolation and biological properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057103259346

21 January 2018

Identifiers

DOI

10.1177/1087057103259346

1 reference

6 December 2017

1 reference