(Q44519511)

3 December 2017

title

A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex (English)

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3 December 2017

Thomas D Pollard

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3 December 2017

Sanjay C Panchal

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3 December 2017

Donald A Kaiser

series ordinal

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3 December 2017

Eduardo Torres

series ordinal

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3 December 2017

Michael K Rosen

series ordinal

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3 December 2017

publication date

1 August 2003

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Nature structural biology

3 December 2017

published in

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3 December 2017

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3 December 2017

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3 December 2017

page(s)

591-598

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Actin machinery: pushing the envelope.

3 December 2017

cites work

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Mechanism of actin-based motility.

31 March 2020

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Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia

31 March 2020

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Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.

31 March 2020

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The Arp2/3 complex: a multifunctional actin organizer

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Regulation of Wiskott-Aldrich syndrome protein and related molecules

31 March 2020

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Integration of signals to the Arp2/3 complex

31 March 2020

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Surfing pathogens and the lessons learned for actin polymerization.

31 March 2020

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The Wiskott-Aldrich syndrome

31 March 2020

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Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

31 March 2020

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Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization

31 March 2020

1 reference

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases

31 March 2020

1 reference

Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex

31 March 2020

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Direct binding of the verprolin-homology domain in N-WASP to actin is essential for cytoskeletal reorganization

31 March 2020

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Two tandem verprolin homology domains are necessary for a strong activation of Arp2/3 complex-induced actin polymerization and induction of microspike formation by N-WASP.

31 March 2020

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The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

31 March 2020

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Arp2/3 complex-independent actin regulatory function of WAVE.

31 March 2020

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Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex

31 March 2020

1 reference

Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck

31 March 2020

1 reference

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

31 March 2020

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Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

31 March 2020

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Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex

31 March 2020

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Global disruption of the WASP autoinhibited structure on Cdc42 binding. Ligand displacement as a novel method for monitoring amide hydrogen exchange.

31 March 2020

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Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

31 March 2020

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Improved 3D triple resonance experiments, HNN and HN(C)N, for HN and 15N sequential correlations in (13C, 15N) labeled proteins: application to unfolded proteins

31 March 2020

1 reference

The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data

31 March 2020

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Activation of the Arp2/3 complex by the Listeria acta protein. Acta binds two actin monomers and three subunits of the Arp2/3 complex.

31 March 2020

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31 March 2020

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Quantitative analysis of the effect of Acanthamoeba profilin on actin filament nucleation and elongation

31 March 2020

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Missense mutations of the WASP gene cause intermittent X-linked thrombocytopenia

31 March 2020

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Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of actin assembly

31 March 2020

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Different WASP family proteins stimulate different Arp2/3 complex-dependent actin-nucleating activities

31 March 2020

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Crystal structure of Arp2/3 complex

31 March 2020

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Structure of Arp2/3 complex in its activated state and in actin filament branch junctions

31 March 2020

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Activation of Arp2/3 complex by Wiskott-Aldrich Syndrome protein is linked to enhanced binding of ATP to Arp2.

31 March 2020

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Arp2/3 complex requires hydrolyzable ATP for nucleation of new actin filaments

31 March 2020

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Identification of a factor in conventional muscle actin preparations which inhibits actin filament self-association

31 March 2020

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A Suite of Triple Resonance NMR Experiments for the Backbone Assignment of 15N, 13C, 2H Labeled Proteins with High Sensitivity

31 March 2020

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

31 March 2020

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NMR View: A computer program for the visualization and analysis of NMR data

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSB952

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3 December 2017

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