(Q44502162)

3 December 2017

title

Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis (English)

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3 December 2017

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Jayanta Debnath

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Kenna R Mills

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3 December 2017

Joan S Brugge

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3 December 2017

Mauricio J Reginato

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3 December 2017

Jessica K Paulus

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3 December 2017

Danielle K Lynch

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3 December 2017

Dennis C Sgroi

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3 December 2017

Senthil K Muthuswamy

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3 December 2017

publication date

1 August 2003

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3 December 2017

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3 December 2017

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3 December 2017

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3 December 2017

page(s)

733-740

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3 December 2017

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

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ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

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FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

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Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

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Role of PI3-kinase in Bcl-X induction and apoptosis inhibition mediated by IL-3 or IGF-1 in Baf-3 cells

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Regulation of cell death protease caspase-9 by phosphorylation

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The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal

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Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway

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Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

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Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

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7 January 2021

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

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7 January 2021

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

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7 January 2021

A matter of life and cell death

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7 January 2021

Tissue reconstitution, or transgenic mammary gland, technique for modeling breast cancer development

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A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

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Gene expression profiles of human breast cancer progression

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Identifiers

DOI

10.1038/NCB1026

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3 December 2017

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