(Q44588587)

4 December 2017

title

The RuvAB branch migration complex can displace topoisomerase IV.quinolone.DNA ternary complexes (English)

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4 December 2017

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Molly E Shea

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4 December 2017

Hiroshi Hiasa

series ordinal

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4 December 2017

language of work or name

English

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publication date

17 September 2003

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Journal of Biological Chemistry

4 December 2017

published in

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4 December 2017

volume

278

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4 December 2017

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4 December 2017

page(s)

48485-48490

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Homologous genetic recombination: the pieces begin to fall into place

4 December 2017

cites work

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Recombination by replication

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The importance of repairing stalled replication forks

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Positive torsional strain causes the formation of a four-way junction at replication forks

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Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

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Exchanging partners: recombination in E. coli.

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Processing of recombination intermediates by the RuvABC proteins

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Topoisomerase Poisons: Harnessing the Dark Side of Enzyme Mechanism

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Tumor cell death induced by topoisomerase-targeting drugs.

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Topoisomerase IV is a target of quinolones in Escherichia coli

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DNA strand cleavage is required for replication fork arrest by a frozen topoisomerase-quinolone-DNA ternary complex.

21 January 2018

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The mechanism of inhibition of topoisomerase IV by quinolone antibacterials

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The complex of DNA gyrase and quinolone drugs on DNA forms a barrier to the T7 DNA polymerase replication complex.

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An antitumor drug-induced topoisomerase cleavage complex blocks a bacteriophage T4 replication fork in vivo

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21 January 2018

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Mechanism of quinolone action. A drug-induced structural perturbation of the DNA precedes strand cleavage by topoisomerase IV.

21 January 2018

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21 January 2018

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21 January 2018

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RuvA and RuvB proteins of Escherichia coli exhibit DNA helicase activity in vitro

21 January 2018

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Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

21 January 2018

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Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

21 January 2018

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Cellular responses to DNA damage

21 January 2018

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Homologous recombination near and far from DNA breaks: alternative roles and contrasting views

21 January 2018

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Staphylococcus aureus gyrase-quinolone-DNA ternary complexes fail to arrest replication fork progression in vitro. Effects of salt on the DNA binding mode and the catalytic activity of S. aureus gyrase

21 January 2018

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DNA gyrase-mediated wrapping of the DNA strand is required for the replication fork arrest by the DNA gyrase-quinolone-DNA ternary complex

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M304217200

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4 December 2017

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