(Q44563633)

4 December 2017

title

Design of quinolinedione-based geldanamycin analogues (English)

1 reference

4 December 2017

Luke Whitesell

1 reference

4 December 2017

Robert Hargreaves

1 reference

4 December 2017

Cynthia L David

series ordinal

1 reference

4 December 2017

Edward B Skibo

series ordinal

1 reference

4 December 2017

language of work or name

English

0 references

publication date

1 September 2003

1 reference

Bioorganic & Medicinal Chemistry Letters

4 December 2017

1 reference

inferred from page(s)

published in

1 reference

4 December 2017

1 reference

4 December 2017

1 reference

4 December 2017

page(s)

3075-3078

1 reference

Hsp90 inhibitors as novel cancer chemotherapeutic agents

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Modifying rates of reductive elimination of leaving groups from indolequinone prodrugs: a key factor in controlling hypoxia-selective drug release

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Structure-based 3-D-QSAR analysis of marine indole alkaloids

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin with use of asymmetric anti- and syn-glycolate aldol reactions

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Synthesis of the left-hand portion of geldanamycin using an anti glycolate aldol reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Facile synthesis of a library of 9-alkyl-8-benzyl-9H-purin-6-ylamine derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Heterocyclic quinones. 17. A new in vivo active antineoplastic drug: 6,7-bis(1-aziridinyl)-4-[[3-(N,N-dimethylamino)propyl]amino]-5,8- quinazolinedione

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Aziridinyl quinone antitumor agents based on indoles and cyclopent[b]indoles: structure-activity relationships for cytotoxicity and antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Chemistry and DNA alkylation reactions of aziridinyl quinones: development of an efficient alkylating agent of the phosphate backbone

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

A comprehensive study of the active site residues of DT-diaphorase: rational design of benzimidazolediones as DT-diaphorase substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

Molybdate inhibits hsp90, induces structural changes in its C-terminal domain, and alters its interactions with substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900650-4

7 January 2021

10.1016/S0960-894X(03)00650-4

Identifiers

DOI

1 reference

4 December 2017

1 reference