(Q44466998)

3 December 2017

title

Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells (English)

1 reference

3 December 2017

Alzheimer's Aβ(1–42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells (English)

1 reference

15 November 2024

main subject

Alzheimer's disease

0 references

endoplasmic reticulum

0 references

T. Iwatsubo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9288730

15 November 2024

D. G. Cook

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9288730

15 November 2024

M. S. Forman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9288730

15 November 2024

J. C. Sung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9288730

15 November 2024

S. Leight

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9288730

15 November 2024

D. L. Kolson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9288730

15 November 2024

V. M. Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9288730

15 November 2024

R. W. Doms

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9288730

15 November 2024

language of work or name

English

0 references

publication date

1 September 1997

1 reference

3 December 2017

September 1997

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9288730

full work available at URL

15 November 2024

http://www.nature.com/articles/nm0997-1021

1 reference

http://www.nature.com/articles/nm0997-1021.pdf

15 November 2024

file format

Portable Document Format

1 reference

15 November 2024

1 reference

3 December 2017

1 reference

3 December 2017

1 reference

3 December 2017

page(s)

1021-1023

1 reference

Amyloid plaque core protein in Alzheimer disease and Down syndrome

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Pre- and post-Golgi vacuoles operate in the transport of Semliki Forest virus membrane glycoproteins to the cell surface

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Inhibition of β-amyloid formation identifies proteolytic precursors and subcellular site of catabolism

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Light and electron microscopic localization of presenilin-1 in primate brain.

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Expression of foreign proteins in a human neuronal system

1 reference

https://api.crossref.org/works/10.1038%2FNM0997-1021

7 January 2021

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum

1 reference

15 November 2024

Identifiers

DOI

10.1038/NM0997-1021

1 reference

3 December 2017

1 reference