(Q44117460)

30 November 2017

title

Survival of patients with glioblastoma multiforme is not influenced by altered expression of p16, p53, EGFR, MDM2 or Bcl-2 genes (English)

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30 November 2017

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E W Newcomb

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30 November 2017

H Cohen

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30 November 2017

S R Lee

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30 November 2017

S K Bhalla

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30 November 2017

J Bloom

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30 November 2017

R L Hayes

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30 November 2017

D C Miller

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30 November 2017

publication date

1 October 1998

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30 November 2017

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30 November 2017

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30 November 2017

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30 November 2017

page(s)

655-667

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Patient age, histologic features, and length of survival in patients with glioblastoma multiforme.

30 November 2017

cites work

1 reference

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Association of p53 gene mutation with decreased chemosensitivity in human malignant gliomas.

21 January 2018

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Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation

21 January 2018

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Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors.

21 January 2018

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The p53 gene and its role in human brain tumors.

21 January 2018

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Genetic alterations associated with the evolution and progression of astrocytic brain tumours

21 January 2018

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Molecular pathways in the formation of gliomas.

21 January 2018

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Association of EGFR Gene Amplification and CDKN2 (p16/MTS1) Gene Deletion in Glioblastoma Multiforme

21 January 2018

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bcl-2 protein expression in astrocytomas in relation to patient survival and p53 gene status

21 January 2018

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The prognostic impact of prior low grade histology in patients with anaplastic gliomas: a case-control study

21 January 2018

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Subsets of glioblastoma multiforme defined by molecular genetic analysis

21 January 2018

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p53 mutation, expression, and DNA ploidy in evolving gliomas: evidence for two pathways of progression.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

Pattern of mutant p53 expression in human astrocytomas suggests the existence of alternate pathways of tumorigenesis

21 January 2018

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Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas

21 January 2018

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A molecular genetic model of astrocytoma histopathology

21 January 2018

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Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme

21 January 2018

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Necrosis as a prognostic factor in glioblastoma multiforme

21 January 2018

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Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumours

21 January 2018

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Lack of prognostic relevance of alterations in the epidermal growth factor receptor-transforming growth factor-alpha pathway in human astrocytic gliomas

21 January 2018

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Analysis of proliferation markers and p53 expression in gliomas of astrocytic origin: relationships and prognostic value

21 January 2018

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MDM2 and p53 expression in gliomas: a multivariate survival analysis including proliferation markers and epidermal growth factor receptor

21 January 2018

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Prognostic factors in malignant glioma: influence of the overexpression of oncogene and tumor-suppressor gene products on survival

21 January 2018

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A correlative study of p53 protein alteration and p53 gene mutation in glioblastoma multiforme

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

Correlative immunohistochemistry and molecular genetic study of the inactivation of the p16INK4A genes in astrocytomas

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

Analysis of p53 gene mutations in low- and high-grade astrocytomas by polymerase chain reaction-assisted single-strand conformation polymorphism and immunohistochemistry

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

Amplification of Epidermal Growth Factor Receptor Gene in Gliomas: Histopathology and Prognosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00191.X

10.1111/J.1750-3639.1998.TB00191.X

21 January 2018

Identifiers

DOI

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30 November 2017

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