(Q44055107)

29 November 2017

title

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development (English)

1 reference

developmental gene expression regulation

29 November 2017

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9224716

7 November 2024

M. Sander

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9224716

7 November 2024

A. Neubüser

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9224716

7 November 2024

J. Kalamaras

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9224716

7 November 2024

H. C. Ee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9224716

7 November 2024

G. R. Martin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9224716

7 November 2024

M. S. German

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9224716

7 November 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9224716

7 November 2024

publication date

1 July 1997

1 reference

29 November 2017

1 reference

29 November 2017

1 reference

29 November 2017

1 reference

29 November 2017

page(s)

1662-1673

1 reference

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

29 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Characterization of Pax-6 and Hoxa-1 binding to the promoter region of the neural cell adhesion molecule L1

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Transcriptional regulation of the mouse alpha A-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I gene

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

The insulin gene promoter. A simplified nomenclature

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

A novel strategy for constructing clustered point mutations

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Mouse mutations and human disorders are paired

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Mouse small eye results from mutations in a paired-like homeobox-containing gene

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

The human PAX6 gene is mutated in two patients with aniridia

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

The Pancreatic Islet-Specific Glucagon G3 Transcription Factors Recognize Control Elements in the Rat Somatostatin and Insulin-I Genes

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Pax genes and their roles in cell differentiation and development

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Expression of avian Pax1 and Pax9 is intrinsically regulated in the pharyngeal endoderm, but depends on environmental influences in the paraxial mesoderm.

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Insulin-like Growth Factor II Is Focally Up-regulated and Functionally Involved as a Second Signal for Oncogene-induced Tumorigenesis

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Function of the human insulin promoter in primary cultured islet cells

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1.

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Glucagon gene transcription is negatively regulated by insulin in a hamster islet cell line

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Islet-specific proteins interact with the insulin-response element of the glucagon gene

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Pancreatic beta cells express a diverse set of homeobox genes

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

The beta cell transcription factors and development of the pancreas

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Defects of neuronal migration and the pathogenesis of cortical malformations are associated with Small eye (Sey) in the mouse, a point mutation at the Pax-6-locus

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Pax-QNR/Pax-6, a paired box- and homeobox-containing gene expressed in neurons, is also expressed in pancreatic endocrine cells

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

The B cell-specific transcription factor BSAP regulates B cell proliferation

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Pax: a murine multigene family of paired box-containing genes

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Regulation of insulin preRNA splicing by glucose

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

The LIM domain homeobox gene isl-1 is a positive regulator of islet cell-specific proglucagon gene transcription

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Structure of the human glucagon gene

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

7 November 2024

1 reference

https://api.crossref.org/works/10.1101/GAD.11.13.1662

7 November 2024

Identifiers

DOI

1 reference

29 November 2017

1 reference