(Q44047581)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Oxidation of methoxyphenethylamines by cytochrome P450 2D6. Analysis of rate-limiting steps (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

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10 November 2019

F Peter Guengerich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Imad H Hanna

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Hideaki Sato

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Martha V Martin

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

language of work or name

English

0 references

publication date

1 July 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

10 November 2019

published in

1 reference

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10 November 2019

volume

277

1 reference

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10 November 2019

issue

1 reference

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10 November 2019

page(s)

33711-33719

1 reference

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Steady-state analysis of kinetic isotope effects in enzymic reactions

10 November 2019

cites work

1 reference

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Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase

21 January 2018

1 reference

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Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

21 January 2018

1 reference

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Oxygen activation by cytochrome P-450.

21 January 2018

1 reference

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Kinetics of Ferric Cytochrome P450 Reduction by NADPH−Cytochrome P450 Reductase: Rapid Reduction in the Absence of Substrate and Variations among Cytochrome P450 Systems

21 January 2018

1 reference

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Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Oxidation of substituted N,N-dimethylanilines by cytochrome P-450: estimation of the effective oxidation-reduction potential of cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Polymorphic hydroxylation of Debrisoquine in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Pharmacogenomics: translating functional genomics into rational therapeutics

21 January 2018

1 reference

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Heterologous expression of cytochrome P450 2D6 mutants, electron transfer, and catalysis of bufuralol hydroxylation: the role of aspartate 301 in structural integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Diversity in mechanisms of substrate oxidation by cytochrome P450 2D6. Lack of an allosteric role of NADPH-cytochrome P450 reductase in catalytic regioselectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Coumarin substrates for cytochrome P450 2D6 fluorescence assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Dopamine formation from tyramine by CYP2D6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Product dependence of deuterium isotope effects in enzyme-catalyzed reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Influence of amino acid residue 374 of cytochrome P-450 2D6 (CYP2D6) on the regio- and enantio-selective metabolism of metoprolol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Analysis of numerical methods for computer simulation of kinetic processes: development of KINSIM--a flexible, portable system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Numerical integration of rate equations by computer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Analysis of progress curves by simulations generated by numerical integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

A new spectral intermediate associated with cytochrome P-450 function in liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Spectral intermediates in the reaction of oxygen with purified liver microsomal cytochrome P-450

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Kinetic isotope effects and 'metabolic switching' in cytochrome P450-catalyzed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Highly purified microsomal P-450: The oxyferro intermediate stabilized at low temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Peroxo-iron and oxenoid-iron species as alternative oxygenating agents in cytochrome P450-catalyzed reactions: switching by threonine-302 to alanine mutagenesis of cytochrome P450 2B4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Atypical kinetic profiles in drug metabolism reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Polymorphic variants (CYP2C9*3 and CYP2C9*5) and the F114L active site mutation of CYP2C9: effect on atypical kinetic metabolism profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

On the mechanism of 11-hydroxylation of lauric acid by rat liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205146200

21 January 2018

Identifiers

DOI

10.1074/JBC.M205146200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093814%20AND%20SRC:MED&resulttype=core&format=json