(Q43866084)

27 November 2017

title

A role of Rab7 in stabilizing EGFR-Her2 and in sustaining Akt survival signal (English)

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27 November 2017

Tuanlao Wang

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27 November 2017

Ming Zhang

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27 November 2017

Zexu Ma

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27 November 2017

Ke Guo

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27 November 2017

Vinay Tergaonkar

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27 November 2017

Qi Zeng

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27 November 2017

Wanjin Hong

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27 November 2017

publication date

1 June 2012

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Journal of Cellular Physiology

27 November 2017

published in

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27 November 2017

volume

227

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27 November 2017

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27 November 2017

page(s)

2788-2797

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cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

27 November 2017

cites work

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Activation of the AKT and STAT3 pathways and prolonged survival by a mutant EGFR in human lung cancer cells.

21 January 2018

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Synaptic protein degradation by the ubiquitin proteasome system

21 January 2018

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The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

21 January 2018

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Rab7: a key to lysosome biogenesis

21 January 2018

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Small molecule epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small cell lung cancer.

21 January 2018

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rab7 activity affects epidermal growth factor:epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome

21 January 2018

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The role of ARF and Rab GTPases in membrane transport

21 January 2018

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The Hsp90 chaperone complex regulates GDI-dependent Rab recycling

21 January 2018

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Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors

21 January 2018

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The regulatory mechanisms of export trafficking of G protein-coupled receptors.

21 January 2018

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Growth factors regulate cell survival by controlling nutrient transporter expression

21 January 2018

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Rab7 Prevents Growth Factor-Independent Survival by Inhibiting Cell-Autonomous Nutrient Transporter Expression

21 January 2018

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Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

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Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants

21 January 2018

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Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

21 January 2018

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The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome

21 January 2018

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Proteasome inhibition blocks ligand-induced dynamic processing and internalization of epidermal growth factor receptor via altered receptor ubiquitination and phosphorylation

21 January 2018

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Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

21 January 2018

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Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation

21 January 2018

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Anoikis: cancer and the homeless cell

21 January 2018

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Go outside and see the proteasome. Protein degradation

21 January 2018

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Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

21 January 2018

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PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

21 January 2018

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Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non small cell lung cancer cell line

21 January 2018

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Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest

21 January 2018

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Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins

21 January 2018

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Rab GTPases: specifying and deciphering organelle identity and function

21 January 2018

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21 January 2018

Endocytosis and cancer.

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Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

21 January 2018

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Rab7 activation by growth factor withdrawal contributes to the induction of apoptosis

21 January 2018

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Anti-EGFR monoclonal antibodies in the treatment of non-small cell lung cancer.

21 January 2018

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Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxel

21 January 2018

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Herbimycin A induces the 20 S proteasome- and ubiquitin-dependent degradation of receptor tyrosine kinases

21 January 2018

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Ypt and Rab GTPases: insight into functions through novel interactions

21 January 2018

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Inhibitors of the HSP90 molecular chaperone: current status

21 January 2018

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Epidermal growth factor receptors harboring kinase domain mutations associate with the heat shock protein 90 chaperone and are destabilized following exposure to geldanamycins

21 January 2018

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A Role for Rab7 GTPase in Growth Factor-Regulated Cell Nutrition and Apoptosis

21 January 2018

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The activation of Akt/PKB signaling pathway and cell survival.

21 January 2018

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Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11

21 January 2018

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Endocytosis of growth factor receptors

21 January 2018

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The ubiquitin-proteasome pathway and the regulation of growth hormone receptor availability

21 January 2018

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A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

21 January 2018

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Design and cloning of lentiviral vectors expressing small interfering RNAs

21 January 2018

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Production and purification of lentiviral vectors

21 January 2018

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Akt is frequently activated in HER2/neu-positive breast cancers and associated with poor prognosis among hormone-treated patients

21 January 2018

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Rab11 regulates recycling through the pericentriolar recycling endosome

21 January 2018

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EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity

21 January 2018

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Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein

21 January 2018

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Rab proteins as membrane organizers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.23023

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27 November 2017

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