(Q43566798)

24 November 2017

title

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. (English)

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24 November 2017

Bunnell SC

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24 November 2017

Kapoor V

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24 November 2017

Trible RP

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24 November 2017

Zhang W

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24 November 2017

Samelson LE

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24 November 2017

language of work or name

English

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publication date

1 March 2001

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24 November 2017

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24 November 2017

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24 November 2017

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24 November 2017

page(s)

315-329

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Rho regulates T cell receptor ITAM-induced lymphocyte spreading in an integrin-independent manner

24 November 2017

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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

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Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton

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The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

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Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism

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7 January 2021

Translocation and clustering of endosomes and lysosomes depends on microtubules

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7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

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7 January 2021

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7 January 2021

Rho GTPases control polarity, protrusion, and adhesion during cell movement

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7 January 2021

Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment

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7 January 2021

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7 January 2021

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7 January 2021

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

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7 January 2021

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

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7 January 2021

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7 January 2021

Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts

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7 January 2021

Actin dynamics in vivo.

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7 January 2021

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

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7 January 2021

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

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7 January 2021

Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

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7 January 2021

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

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7 January 2021

Essential role of LAT in T cell development

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7 January 2021

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

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7 January 2021

How WASP regulates actin polymerization

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7 January 2021

10.1016/S1074-7613(01)00112-1

Identifiers

DOI

1 reference

24 November 2017

1 reference