(Q43276048)

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Homology modelling of the human adenosine A2B receptor based on X-ray structures of bovine rhodopsin, the beta2-adrenergic receptor and the human adenosine A2A receptor

scientific article published in November 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Homology modelling of the human adenosine A2B receptor based on X-ray structures of bovine rhodopsin, the beta2-adrenergic receptor and the human adenosine A2A receptor (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Anke C Schiedel

2

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Christa E Müller

4

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

author name string

Farag F Sherbiny

1

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Astrid Maass

3

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

publication date

1 November 2009

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Journal of Computer - Aided Molecular Design

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

807-828

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

Adenosine receptor ligands-recent developments part I. Agonists

1 reference

https://api.crossref.org/works/10.1007%2FS10822-009-9299-7

21 January 2018

Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10822-009-9299-7

21 January 2018

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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Water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, A(2A)-selective adenosine receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Substituted adenosine derivatives: affinity and efficacy at four subtypes of human adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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Towards a revised nomenclature for P1 and P2 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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How many drug targets are there?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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Crystal structure of the ligand-free G-protein-coupled receptor opsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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Molecular tinkering of G protein-coupled receptors: an evolutionary success

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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Site-directed mutagenesis of the human adenosine A2A receptor. Critical involvement of Glu13 in agonist recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KW-6002 (Kyowa Hakko Kogyo).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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On the accuracy of homology modeling and sequence alignment methods applied to membrane proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

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Medicinal chemistry and pharmacology of A2B adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statistical sequence analyses of G-protein-coupled receptors: structural and functional characteristics viewed with periodicities of entropy, hydrophobicity, and volume

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening drug-like compounds by docking to homology models: a systematic study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereochemical quality of protein structure coordinates

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate residues in the second extracellular loop of the human A2a adenosine receptor are required for ligand recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrophilic side chains in the third and seventh transmembrane helical domains of human A2A adenosine receptors are required for ligand recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computer aided comparative analysis of the binding modes of the adenosine receptor agonists for all known subtypes of adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of a homology model of the human histamine H3 receptor for ligand docking and pharmacophore-based screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Random mutagenesis of the human adenosine A2B receptor followed by growth selection in yeast. Identification of constitutively active and gain of function mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-directed mutagenesis studies of human A(2A) adenosine receptors: involvement of glu(13) and his(278) in ligand binding and sodium modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A graph-theory algorithm for rapid protein side-chain prediction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Quintiles Prize Lecture 2004. The identification of the adenosine A2B receptor as a novel therapeutic target in asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the Potent and Highly Selective A(2A) Receptor Antagonists Preladenant and SCH 412348 [7-[2-[4-2,4-Difluorophenyl]-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyraz olo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine] in Rodent Models of

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the utility of homology models in high throughput docking

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reno-vascular A2B adenosine receptor protects the kidney from ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of a diverse set of ligands to avidin and streptavidin: an accurate quantitative prediction of their relative affinities by a combination of molecular mechanics and continuum solvent models

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ranking ligand binding affinities with avidin: a molecular dynamics-based interaction energy study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural diversity of G protein-coupled receptors and significance for drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and biological evaluation of novel 1-deoxy-1-[6-[((hetero)arylcarbonyl)hydrazino]- 9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide derivatives as useful templates for the development of A2B adenosine receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry of transmembrane signaling mediated by trimeric G proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fast flexible docking method using an incremental construction algorithm.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of errors in three-dimensional structures of proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and receptor affinity of polysubstituted adenosines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple automatic base selection: protein-ligand docking based on incremental construction without manual intervention.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homology model-based virtual screening for GPCR ligands using docking and target-biased scoring.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular dynamics simulations of bovine rhodopsin: influence of protonation states and different membrane-mimicking environments

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenesis Reveals Structure−Activity Parallels between Human A2AAdenosine Receptors and Biogenic Amine G Protein-Coupled Receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular modeling and molecular dynamics simulation of the human A2B adenosine receptor. The study of the possible binding modes of the A2B receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure selection for protein kinase docking and virtual screening: homology models or crystal structures?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19757091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10822-009-9299-7

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

DBLP publication ID

journals/jcamd/SherbinySMM09

1 reference

DBLP Dataset 2021-01-02

28 January 2021

Dimensions Publication ID

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release_nwexcclogng65cfvk52fniagfu

1 reference

https://api.fatcat.wiki/v0/release/nwexcclogng65cfvk52fniagfu

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 November 2017

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