(Q42826655)

8 November 2017

title

Mishandling of the therapeutic peptide glucagon generates cytotoxic amyloidogenic fibrils (English)

1 reference

8 November 2017

0 references

1 reference

Satomi Onoue

1 reference

8 November 2017

Keiichi Ohshima

1 reference

8 November 2017

Kazuhiro Debari

1 reference

8 November 2017

Keitatsu Koh

1 reference

8 November 2017

Seiji Shioda

1 reference

8 November 2017

Sumiko Iwasa

1 reference

8 November 2017

Kazuhisa Kashimoto

1 reference

8 November 2017

Takehiko Yajima

1 reference

8 November 2017

publication date

1 July 2004

1 reference

8 November 2017

published in

Pharmaceutical Research

1 reference

8 November 2017

1 reference

8 November 2017

1 reference

8 November 2017

page(s)

1274-1283

1 reference

Immunization against Alzheimer's beta -amyloid plaques via EFRH phage administration

8 November 2017

cites work

1 reference

12 December 2020

Fluorescent molecular probes V: a sensitive caspase-3 substrate for fluorometric assays

1 reference

12 December 2020

Thermal stability: a means to assure tertiary structure in therapeutic proteins.

1 reference

12 December 2020

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

1 reference

12 December 2020

Formation and Structure of Gels and Fibrils from Glucagon

1 reference

12 December 2020

The neuromodulatory effects of VIP/PACAP on PC-12 cells are associated with their N-terminal structures

1 reference

12 December 2020

Amyloid deposits and amyloidosis: the beta-fibrilloses (second of two parts).

1 reference

12 December 2020

Computed circular dichroism spectra for the evaluation of protein conformation

1 reference

12 December 2020

Aggregation pathway of recombinant human keratinocyte growth factor and its stabilization

1 reference

12 December 2020

Amino acid composition of salmon calcitonin.

1 reference

12 December 2020

Conformational transitions and fibrillation mechanism of human calcitonin as studied by high-resolution solid-state 13C NMR

1 reference

12 December 2020

Neurotoxicity of a prion protein fragment

1 reference

12 December 2020

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

1 reference

12 December 2020

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

1 reference

12 December 2020

Effects of non-covalent self-association on the subcutaneous absorption of a therapeutic peptide.

1 reference

12 December 2020

Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide

1 reference

12 December 2020

Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.

1 reference

12 December 2020

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

12 December 2020

The reaction of glucagon with its receptor: evidence for discrete regions of activity and binding in the glucagon molecule

1 reference

12 December 2020

1 reference

12 December 2020

The neuropeptide PACAP attenuates beta-amyloid (1-42)-induced toxicity in PC12 cells

1 reference

12 December 2020

Immunomodulation of the human prion peptide 106-126 aggregation

1 reference

12 December 2020

Cross- protein structures. I. Insulin fibrils

1 reference

12 December 2020

Binding of the dye congo red to the amyloid protein pig insulin reveals a novel homology amongst amyloid-forming peptide sequences

1 reference

12 December 2020

Comparison of the aggregation properties, secondary structure and apoptotic effects of wild-type, Flemish and Dutch N-terminally truncated amyloid beta peptides

1 reference

12 December 2020

Amyloidogenic determinant as a substrate recognition motif of insulin-degrading enzyme

1 reference

12 December 2020

Cyclic nucleotides suppress tumor necrosis factor alpha-mediated apoptosis by inhibiting caspase activation and cytochrome c release in primary hepatocytes via a mechanism independent of Akt activation

1 reference

12 December 2020

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

1 reference

12 December 2020

Medicine: danger--misfolding proteins.

1 reference

12 December 2020

Enhancement of MTT, a tetrazolium salt, exocytosis by amyloid beta-protein and chloroquine in cultured rat astrocytes

1 reference

12 December 2020

Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation

1 reference

12 December 2020

Two simple methods for quantifying low-affinity dye-substrate binding.

1 reference

12 December 2020

Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts).

1 reference

12 December 2020

Solid-phase peptide synthesis

1 reference

12 December 2020

Structure of Porcine Secretin. The Amino Acid Sequence

1 reference

12 December 2020

X-ray analysis of glucagon and its relationship to receptor binding

1 reference

12 December 2020

Alzheimer's disease--from cause to cure?

1 reference

12 December 2020

PACAP protects neuronal PC12 cells from the cytotoxicity of human prion protein fragment 106-126.

1 reference

12 December 2020

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

1 reference

12 December 2020

Beta-structure in human amylin and two designer beta-peptides: CD and NMR spectroscopic comparisons suggest soluble beta-oligomers and the absence of significant populations of beta-strand dimers

1 reference

12 December 2020

Steroid hormones block amyloid fibril-induced 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) formazan exocytosis: relationship to neurotoxicity.

1 reference

12 December 2020

1 reference

12 December 2020

Cyclic-AMP inhibits nitric oxide-induced apoptosis in human osteoblast: the regulation of caspase-3, -6, -9 and the release of cytochrome c in nitric oxide-induced apoptosis by cAMP.

1 reference

12 December 2020

10.1023/B:PHAM.0000033016.36825.2C

Identifiers

DOI

1 reference

8 November 2017

1 reference