(Q42815794)

7 November 2017

title

VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells (English)

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7 November 2017

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T Takahashi

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7 November 2017

H Ueno

series ordinal

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7 November 2017

M Shibuya

series ordinal

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7 November 2017

language of work or name

English

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publication date

1 April 1999

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7 November 2017

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7 November 2017

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7 November 2017

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7 November 2017

page(s)

2221-2230

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Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

7 November 2017

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7 January 2021

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product

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7 January 2021

Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

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7 January 2021

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

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High levels of biologically active vascular endothelial growth factor (VEGF) are produced by the baculovirus expression system

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7 January 2021

Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding

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7 January 2021

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis

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7 January 2021

Tumor-promoting phorbol esters stimulate bovine cerebral cortex capillary endothelial cell growth in vitro

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7 January 2021

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

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7 January 2021

Two molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development

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7 January 2021

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

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7 January 2021

The vascular endothelial growth factor family of polypeptides

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7 January 2021

What Is the Evidence That Tumors Are Angiogenesis Dependent?

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7 January 2021

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

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7 January 2021

Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity

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7 January 2021

Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells

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7 January 2021

Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation.

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7 January 2021

Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation

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7 January 2021

Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues

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7 January 2021

Two types of RAS mutants that dominantly interfere with activators of RAS.

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7 January 2021

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Roles of PI 3-kinase and Ras on insulin-stimulated glucose transport in 3T3-L1 adipocytes

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7 January 2021

Vascular permeability factor, an endothelial cell mitogen related to PDGF

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7 January 2021

Protein kinase C alpha activates RAF-1 by direct phosphorylation

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7 January 2021

The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

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7 January 2021

Vascular endothelial growth factor is a secreted angiogenic mitogen

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7 January 2021

The Ras-JNK pathway is involved in shear-induced gene expression

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7 January 2021

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit

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7 January 2021

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

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7 January 2021

Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome

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7 January 2021

Localization of protein kinases by anchoring proteins: a theme in signal transduction

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7 January 2021

Tumor-promoting phorbol esters induce angiogenesis in vitro

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7 January 2021

Tumor-promoting phorbol esters induce angiogenesis in vivo

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7 January 2021

Endothelial receptor tyrosine kinases involved in angiogenesis.

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7 January 2021

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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7 January 2021

Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells

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7 January 2021

NGF and EGF rapidly activate p21ras in PC12 cells by distinct, convergent pathways involving tyrosine phosphorylation

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7 January 2021

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

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7 January 2021

Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells

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7 January 2021

Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity

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7 January 2021

The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCgamma

1 reference

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7 January 2021

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

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7 January 2021

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

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7 January 2021

Angiotensin II stimulates mitogen-activated protein kinases and protein synthesis by a Ras-independent pathway in vascular smooth muscle cells

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7 January 2021

The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-gamma pathway and partially induces mitotic signals in NIH3T3 fibroblasts

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7 January 2021

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202527

7 January 2021

Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202527

7 January 2021

Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202527

7 January 2021

Diacylglycerol accumulation and microvascular abnormalities induced by elevated glucose levels

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202527

7 January 2021

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202527

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202527

1 reference

Dimensions Publication ID

7 November 2017

1028845715

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1 reference