(Q42809404)

7 November 2017

title

Protein kinase C-alpha regulates insulin action and degradation by interacting with insulin receptor substrate-1 and 14-3-3 epsilon (English)

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7 November 2017

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7 November 2017

Francesco Oriente

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7 November 2017

Francesco Andreozzi

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7 November 2017

Chiara Romano

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7 November 2017

Giuseppe Perruolo

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7 November 2017

Anna Perfetti

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7 November 2017

Francesca Fiory

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7 November 2017

Claudia Miele

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7 November 2017

Francesco Beguinot

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7 November 2017

language of work or name

English

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publication date

10 October 2005

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Journal of Biological Chemistry

7 November 2017

published in

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7 November 2017

volume

280

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7 November 2017

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7 November 2017

page(s)

40642-40649

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Insulin signal transduction through protein kinase cascades

7 November 2017

cites work

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21 January 2018

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Positive and negative regulatory role of insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) serine/threonine phosphorylation.

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Protein kinase C isoforms beta 1 and beta 2 inhibit the tyrosine kinase activity of the insulin receptor

21 January 2018

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Protein kinase C isoforms alpha, delta and theta require insulin receptor substrate-1 to inhibit the tyrosine kinase activity of the insulin receptor in human kidney embryonic cells (HEK 293 cells).

21 January 2018

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Insulin-induced Akt activation is inhibited by angiotensin II in the vasculature through protein kinase C-alpha

21 January 2018

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An overview of endothelin signaling in the cardiac myocyte

21 January 2018

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Chronic endothelin-1 treatment leads to insulin resistance in vivo

21 January 2018

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Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism

21 January 2018

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In L6 skeletal muscle cells, glucose induces cytosolic translocation of protein kinase C-alpha and trans-activates the insulin receptor kinase

21 January 2018

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Knockout of PKC alpha enhances insulin signaling through PI3K

21 January 2018

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Protein kinase C isozyme selective peptides--a current view of what they tell us about location and function of isozymes in the heart.

21 January 2018

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Protein kinase C activation and the development of diabetic complications

21 January 2018

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Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply

21 January 2018

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Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes

21 January 2018

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Rapid and Long Term Effects of Protein Kinase C on Receptor Tyrosine Kinase Phosphorylation and Degradation

21 January 2018

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Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase.

21 January 2018

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Functional interaction of protein kinase Calpha with the tyrosine kinases Syk and Src in human platelets.

21 January 2018

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In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing

21 January 2018

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Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells

21 January 2018

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Protein kinase C-zeta and protein kinase B regulate distinct steps of insulin endocytosis and intracellular sorting

21 January 2018

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Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells.

21 January 2018

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The role of protein kinase C in insulin action

21 January 2018

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Requirement of Protein Kinase Cζ for Stimulation of Protein Synthesis by Insulin

21 January 2018

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The role of protein kinase C isoforms in insulin action

21 January 2018

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Insulin induces specific interaction between insulin receptor and protein kinase C delta in primary cultured skeletal muscle

21 January 2018

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Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins

21 January 2018

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14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.

21 January 2018

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14-3-3 (epsilon) interacts with the insulin-like growth factor I receptor and insulin receptor substrate I in a phosphoserine-dependent manner

21 January 2018

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A partial catalog of proteins secreted by epidermal keratinocytes in culture

21 January 2018

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14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity

21 January 2018

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14-3-3 proteins: key regulators of cell division, signalling and apoptosis.

21 January 2018

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Protein kinase C inhibitor proteins. Purification from sheep brain and sequence similarity to lipocortins and 14-3-3 protein

21 January 2018

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Activation of protein kinase C by the 14-3-3 proteins homologous with Exo1 protein that stimulates calcium-dependent exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508570200

Protein kinase C activation by acidic proteins including 14-3-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508570200

14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508570200

Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508570200

21 January 2018

Identifiers

DOI

10.1074/JBC.M508570200

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7 November 2017

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