(Q42803654)

7 November 2017

title

Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformation (English)

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7 November 2017

R A Rimerman

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7 November 2017

A Gellert-Randleman

series ordinal

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7 November 2017

J A Diehl

series ordinal

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7 November 2017

language of work or name

English

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publication date

1 May 2000

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Journal of Biological Chemistry

7 November 2017

published in

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7 November 2017

volume

275

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7 November 2017

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7 November 2017

page(s)

14736-14742

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WNTs modulate cell fate and behavior during vertebrate development

7 November 2017

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1 reference

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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How do small GTPase signal transduction pathways regulate cell cycle entry?

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Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

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Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis

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GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis

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Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

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Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

21 January 2018

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Cyclin D1 is a nuclear protein required for cell cycle progression in G1

21 January 2018

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Coupling of the cell cycle and myogenesis through the cyclin D1-dependent interaction of MyoD with cdk4

21 January 2018

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Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

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Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

21 January 2018

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Oncogenic collaboration of the cyclin D1 (PRAD1, bcl-1) gene with a mutated p53 and an activated ras oncogene in neoplastic transformation.

21 January 2018

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Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

21 January 2018

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APC mutations occur early during colorectal tumorigenesis

21 January 2018

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Lessons from hereditary colorectal cancer

21 January 2018

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Association of the APC gene product with beta-catenin

21 January 2018

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

21 January 2018

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M910241199

1 reference

7 November 2017

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