(Q42760363)

6 November 2017

title

Platensimycin and platencin congeners from Streptomyces platensis (English)

1 reference

6 November 2017

Platensimycin and Platencin Congeners from Streptomyces platensis (English)

1 reference

21 November 2024

1 reference

14-hydroxyplatensic acid methyl ester

68239

1 reference

1 reference

platensimycin B4 methyl ester

68246

1 reference

platensimycin A1 methyl ester

68240

1 reference

platencin A2 methyl ester

68243

1 reference

68252

14-hydroxyplatensic acid

1 reference

1 reference

1 reference

platensimycin A4 methyl ester

68247

1 reference

2 references

platensimycin A3 methyl ester

2 references

platencin A1 methyl ester

1 reference

2 references

platensimycin A5 methyl ester

1 reference

1 reference

platensimycin A2 methyl ester

68249

1 reference

1 reference

platensimycin methyl ester

68245

1 reference

13-hydroxyplatencinic acid methyl ester

68237

1 reference

1 reference

platencin A3 methyl ester

68242

1 reference

1 reference

platensic acid methyl ester

68238

1 reference

2 references

1 reference

2 references

2 references

Streptomyces platensis

1 reference

Platensimycin A5 methyl ester

1 reference

3-[3-(5,9-Dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoylamino]-2,4-dihydroxybenzamide

1 reference

12-hydroxyplatencinic acid methyl ester

1 reference

3-(5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)-N-(7-hydroxy-2,4-dioxo-1,3-benzoxazin-8-yl)propanamide

1 reference

2,4-dihydroxy-3-[3-[(1S,5S,10S)-10-hydroxy-10-(hydroxymethyl)-5-methyl-4-oxo-5-tricyclo[7.2.1.01,6]dodec-2-enyl]propanoylamino]benzoic acid

1 reference

1 reference

NCGC00380429-01_C17H22O4_3-(5,9-Dimethyl-4-oxo-8-oxatetracyclo[7.2.1.1~7,10~.0~1,6~]tridec-2-en-5-yl)propanoic acid

1 reference

2,4-Dihydroxy-3-[3-(12-hydroxy-5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoylamino]benzoic acid

1 reference

Methyl 3-[3-(5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoylamino]-2-hydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoate

1 reference

3-(4-(2-(4-(2-Hydroxy-3-methoxypropoxy)phenyl)propan-2-yl)phenoxy)propane-1,2-diol

1 reference

Methyl 3-(12-hydroxy-5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoate

1 reference

Platensimycin A6 methyl ester

1 reference

4-Acetamido-2-[3-(5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoylamino]butanoic acid

1 reference

Methyl 2,4-dihydroxy-3-[3-(11-hydroxy-5-methyl-9-methylidene-4-oxo-5-tricyclo[6.2.2.01,6]dodec-2-enyl)propanoylamino]benzoate

1 reference

NCGC00384937-01_C17H22O5_3-(12-Hydroxy-5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.1~7,10~.0~1,6~]tridec-2-en-5-yl)propanoic acid

1 reference

1 reference

Platencin A11 methyl ester

1 reference

2,4-Dihydroxy-3-[3-(11-hydroxy-5-methyl-9-methylidene-4-oxo-5-tricyclo[6.2.2.01,6]dodec-2-enyl)propanoylamino]benzoic acid

1 reference

1 reference

5-Amino-2-[[5-(5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)-2-methylpent-2-enoyl]amino]-5-oxopentanoic acid

1 reference

Platencinic acid glycerol ester

1 reference

Platensimycin A4 methyl ester

1 reference

1 reference

Platensimycin A2 methyl ester

1 reference

N-(2,6-dihydroxyphenyl)-3-(5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanamide

1 reference

3-[3-(5,9-Dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoylamino]-2-hydroxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoic acid

1 reference

13R-hydroxyplatencinic acid methyl ester

1 reference

Methyl 2,4-dihydroxy-3-[3-(12-hydroxy-5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoylamino]benzoate

1 reference

13-Hydroxyplatencinic acid

1 reference

2,4-dihydroxy-3-[3-[(1R,2R,5S,7S,9S)-2-hydroxy-5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridecan-5-yl]propanoylamino]benzoic acid

1 reference

Methyl 3-[3-(5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoylamino]-2,4-dihydroxybenzoate

1 reference

Methyl 5-amino-2-[[5-(5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)-2-methylpent-2-enoyl]amino]-5-oxopentanoate

1 reference

Methyl 2,4-dihydroxy-3-[3-(10-hydroxy-5-methyl-9-methylidene-4-oxo-5-tricyclo[6.2.2.01,6]dodec-2-enyl)propanoylamino]benzoate

1 reference

Methyl 3-(5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoate

1 reference

Methyl 2,4-dihydroxy-3-[3-(9-hydroxy-5-methyl-12-methylidene-4-oxo-5-tricyclo[6.2.2.01,6]dodec-2-enyl)propanoylamino]benzoate

1 reference

3-[3-(3,12-Dihydroxy-5,9-dimethyl-4-oxo-8-oxatetracyclo[7.2.1.17,10.01,6]tridec-2-en-5-yl)propanoylamino]-2,4-dihydroxybenzoic acid

1 reference

Chaowei Zhang

1 reference

6 November 2017

John Ondeyka

1 reference

6 November 2017

Kithsiri Herath

1 reference

6 November 2017

Hiranthi Jayasuriya

1 reference

6 November 2017

Ziqiang Guan

1 reference

6 November 2017

Lisa Dietrich

1 reference

6 November 2017

Bruce Burgess

1 reference

6 November 2017

Jun Wang

1 reference

6 November 2017

Deborah L. Zink

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21214253

21 November 2024

Sookhee N. Ha

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21214253

21 November 2024

Sheo B. Singh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21214253

21 November 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21214253

21 November 2024

publication date

7 January 2011

1 reference

full work available at URL

6 November 2017

https://pubs.acs.org/doi/pdf/10.1021/np100635f

1 reference

Journal of Natural Products

21 November 2024

published in

1 reference

6 November 2017

1 reference

6 November 2017

1 reference

6 November 2017

page(s)

329-340

1 reference

Invasive methicillin-resistant Staphylococcus aureus infections in the United States

6 November 2017

cites work

1 reference

Empirical antibacterial drug discovery--foundation in natural products

21 November 2024

1 reference

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

21 November 2024

1 reference

Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy

21 November 2024

1 reference

Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad-Spectrum Antibiotic Activity

21 November 2024

1 reference

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

21 November 2024

1 reference

Discovery of FabH/FabF inhibitors from natural products

21 November 2024

1 reference

Synthesis and biological evaluation of platensimycin analogs

21 November 2024

1 reference

Platensimycin: a promising antimicrobial targeting fatty acid synthesis.

21 November 2024

1 reference

From nature to the laboratory and into the clinic

21 November 2024

1 reference

Total synthesis of platensimycin and related natural products

21 November 2024

1 reference

Adamantaplatensimycin: a bioactive analogue of platensimycin

21 November 2024

1 reference

Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity

21 November 2024

1 reference

7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin: more potent analogs of platensimycin

21 November 2024

1 reference

Total synthesis of (+/-)-platencin

21 November 2024

1 reference

Short formal synthesis of (-)-platencin

21 November 2024

1 reference

Structure and Semisynthesis of Platensimide A, Produced byStreptomyces platensis

21 November 2024

1 reference

Structure of homoplatensimide A: a potential key biosynthetic intermediate of platensimycin isolated from Streptomyces platensis

21 November 2024

1 reference

Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1-B3 from Streptomyces platensis

21 November 2024

1 reference

Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis

21 November 2024

1 reference

Isolation, enzyme-bound structure, and activity of platensimycin A1 from Streptomyces platensis

21 November 2024

1 reference

Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis

21 November 2024

1 reference

Isolation, structure and biological activities of platencin A(2)-A(4) from Streptomyces platensis

21 November 2024

1 reference

21 November 2024

1 reference

Drug discovery beyond the 'rule-of-five'.

21 November 2024

1 reference

Engineering of Streptomyces platensis MA7339 for overproduction of platencin and congeners.

21 November 2024

1 reference

Biosynthetic studies of platensimycin

21 November 2024

1 reference

Determination of selectivity and efficacy of fatty acid synthesis inhibitors

21 November 2024

1 reference

21 November 2024

Identifiers

DOI

10.1021/NP100635F

1 reference

6 November 2017

1 reference