(Q42624915)

3 November 2017

title

Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change (English)

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3 November 2017

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3 November 2017

Peter D Keightley

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3 November 2017

publication date

17 June 2009

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Molecular Biology and Evolution

3 November 2017

published in

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3 November 2017

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3 November 2017

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3 November 2017

page(s)

2097-2108

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Population history and natural selection shape patterns of genetic variation in 132 genes

3 November 2017

cites work

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Adaptive evolution of non-coding DNA in Drosophila

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Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome

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Widely distributed noncoding purifying selection in the human genome

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21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Selection, recombination and demographic history in Drosophila miranda

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

More genes underwent positive selection in chimpanzee evolution than in human evolution

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

The genomic rate of adaptive amino acid substitution in Drosophila.

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Assessing the evolutionary impact of amino acid mutations in the human genome

21 January 2018

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MAVID: constrained ancestral alignment of multiple sequences

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Estimation of hominoid ancestral population sizes under bayesian coalescent models incorporating mutation rate variation and sequencing errors

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

The rate of adaptive evolution in enteric bacteria

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

The other side of the nearly neutral theory, evidence of slightly advantageous back-mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

The McDonald-Kreitman test and slightly deleterious mutations

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Initial sequence of the chimpanzee genome and comparison with the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

The genomic rate of adaptive evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

High genomic deleterious mutation rates in hominids

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

The distribution of fitness effects of new deleterious amino acid mutations in humans

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Genomic selective constraints in murid noncoding DNA

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Adaptive evolution in humans revealed by the negative correlation between the polymorphism and fixation phases of evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Positive and negative selection on noncoding DNA in Drosophila simulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Ubiquitous selective constraints in the Drosophila genome revealed by a genome-wide interspecies comparison

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

A flexible forward simulator for populations subject to selection and demography

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Population genetics of polymorphism and divergence under fluctuating selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Joint inference of the distribution of fitness effects of deleterious mutations and population demography based on nucleotide polymorphism frequencies

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Evolutionary constraints in conserved nongenic sequences of mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Model of effectively neutral mutations in which selective constraint is incorporated

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Selection in favor of nucleotides G and C diversifies evolution rates and levels of polymorphism at mammalian synonymous sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Molecular evolution and phylogeny of the human AIDS viruses LAV, HTLV-III, and ARV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Pattern of sequence variation across 213 environmental response genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Genomewide spatial correspondence between nonsynonymous divergence and neutral polymorphism reveals extensive adaptation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Patterns of molecular variation and evolution in Drosophila americana and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Adaptive protein evolution at the Adh locus in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Molecular signatures of natural selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Estimating the distribution of selection coefficients from phylogenetic data with applications to mitochondrial and viral DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Evidence for variation in the effective population size of animal mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Evolutionary and Biomedical Insights from the Rhesus Macaque Genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Genome-wide detection and characterization of positive selection in human populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Adaptive genic evolution in the Drosophila genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Adaptive protein evolution in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

High-resolution mapping of expression-QTLs yields insight into human gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

A map of recent positive selection in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Estimating the genomewide rate of adaptive protein evolution in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Divergence and polymorphism under the nearly neutral theory of molecular evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Localizing recent adaptive evolution in the human genome

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

The effects of artificial selection on the maize genome

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

Human SNPs reveal no evidence of frequent positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP119

21 January 2018

Identifiers

DOI

10.1093/MOLBEV/MSP119

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3 November 2017

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