(Q42455980)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

title

Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

F Morandi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

S Bonomini

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

M Hojden

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

V Rizzoli

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

A Bonati

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

publication date

1 March 2004

1 reference

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17 November 2019

1 reference

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17 November 2019

volume

1 reference

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17 November 2019

issue

1 reference

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17 November 2019

page(s)

628-635

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

17 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Map kinase signaling pathways and hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

The roles of signaling by the p42/p44 mitogen-activated protein (MAP) kinase pathway; a potential route to radio- and chemo-sensitization of tumor cells resulting in the induction of apoptosis and loss of clonogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Molecular mechanisms of novel therapeutic approaches for multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Novel therapies targeting the myeloma cell and its bone marrow microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Expression of vascular endothelial growth factor and its receptors in multiple myeloma and other hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Development of anticancer drugs targeting the MAP kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Pharmacological inhibitors of MAPK pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Increased bone marrow microvessel density in newly diagnosed multiple myeloma carries a poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Proliferation of IL-6-independent multiple myeloma does not require the activity of extracellular signal-regulated kinases (ERK1/2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Combined treatment with the checkpoint abrogator UCN-01 and MEK1/2 inhibitors potently induces apoptosis in drug-sensitive and -resistant myeloma cells through an IL-6-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Cell-cycle arrest by PD184352 requires inhibition of extracellular signal-regulated kinases (ERK) 1/2 but not ERK5/BMK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Targeting p38 MAPK inhibits multiple myeloma cell growth in the bone marrow milieu

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

7 January 2021

Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

7 January 2021

The MEK inhibitor, PD98059, reduces survival but does not block acute myeloid leukemia blast maturation in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

7 January 2021

Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

7 January 2021

MEK wars, a new front in the battle against cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

7 January 2021

Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403269

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403269

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 November 2019

1032115202

0 references

Fatcat ID

release_z4xsgdfikvhixma3uxcf4pizii

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/z4xsgdfikvhixma3uxcf4pizii

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14737074%20AND%20SRC:MED&resulttype=core&format=json