(Q42321500)

English

IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells

scientific article published on 13 August 2012

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scholarly article

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Europe PubMed Central

PMC publication ID

26 October 2017

IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells (English)

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Margherita Coccia

object named as

Margherita Coccia

1

0 references

Chris Schiering

object named as

Chris Schiering

3

0 references

6

object named as

Fiona Powrie

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Burkhard Becher

5

object named as

Burkhard Becher

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

author name string

Oliver J Harrison

2

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Mark J Asquith

4

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Kevin J Maloy

7

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

language of work or name

0 references

publication date

13 August 2012

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

209

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

9

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

1595-1609

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt- lymphoid cells

1 reference

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26 October 2017

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

1 reference

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26 October 2017

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

1 reference

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26 October 2017

Interleukin-23 drives intestinal inflammation through direct activity on T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

An innately dangerous balancing act: intestinal homeostasis, inflammation, and colitis-associated cancer

1 reference

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26 October 2017

Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue.

1 reference

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26 October 2017

Expansion of human NK-22 cells with IL-7, IL-2, and IL-1beta reveals intrinsic functional plasticity

1 reference

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26 October 2017

Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease.

1 reference

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26 October 2017

Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome

1 reference

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26 October 2017

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Th17 and regulatory T cells in mediating and restraining inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Inflammatory bowel disease

1 reference

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26 October 2017

IL-1 pathways in inflammation and human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Future biologic targets for IBD: potentials and pitfalls

1 reference

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26 October 2017

The IL-1 family: regulators of immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Induction of intestinal Th17 cells by segmented filamentous bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

An autoinflammatory disease due to homozygous deletion of the IL1RN locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

A protective function for interleukin 17A in T cell-mediated intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Immunological and inflammatory functions of the interleukin-1 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

The inflammasomes: guardians of the body

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Inflammatory bowel disease: clinical aspects and established and evolving therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Interleukin-23 drives innate and T cell-mediated intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

In vitro and in vivo characterization of Helicobacter hepaticus cytolethal distending toxin mutants

1 reference

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26 October 2017

Upregulation of interleukin-12 and -17 in active inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Increased expression of interleukin 17 in inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Expression of interleukin 1 beta and interleukin 1 beta converting enzyme by intestinal macrophages in health and inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Biologic basis for interleukin-1 in disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

1 reference

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26 October 2017

Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease

1 reference

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26 October 2017

Role of interleukin 1 in inflammatory bowel disease--enhanced production during active disease

1 reference

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26 October 2017

Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis

1 reference

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26 October 2017

Evaluation of an interleukin-1 receptor antagonist in the rat acetic acid-induced colitis model

1 reference

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26 October 2017

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

26 October 2017

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

1 reference

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29 May 2018

Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation

1 reference

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29 May 2018

A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

1 reference

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29 May 2018

Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

29 May 2018

The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

17 August 2018

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

1 reference

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17 August 2018

Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

17 August 2018

RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

17 August 2018

ATP drives lamina propria T(H)17 cell differentiation

1 reference

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17 August 2018

MyD88-dependent pathway in T cells directly modulates the expansion of colitogenic CD4+ T cells in chronic colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3428945

17 August 2018

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

1 reference

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17 August 2018

Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice

1 reference

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17 August 2018

IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia

1 reference

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17 August 2018

Tissue interleukin 1 and interleukin-1 receptor antagonist expression in enterocolitis in resistant and susceptible rats.

1 reference

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17 August 2018

Enhanced Th1 and Th17 responses and arthritis severity in mice with a deficiency of myeloid cell-specific interleukin-1 receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imbalance between interleukin-1 agonists and antagonists: relationship to severity of inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 1 in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22891275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.20111453

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 October 2017

ResearchGate publication ID

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