(Q42284125)

English

Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial

scientific article published on 12 July 2013

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scholarly article

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Europe PubMed Central

PubMed publication ID

19 October 2017

Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 October 2017

phase III clinical trial

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inferred from title

Seppo Ylä-Herttuala

2

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Europe PubMed Central

PubMed publication ID

19 October 2017

object named as

Philippe Menei

5

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object named as

David Eckland

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Europe PubMed Central

PubMed publication ID

19 October 2017

author name string

Manfred Westphal

1

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Europe PubMed Central

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19 October 2017

John Martin

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Europe PubMed Central

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19 October 2017

Peter Warnke

4

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Europe PubMed Central

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19 October 2017

Judith Kinley

7

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Europe PubMed Central

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19 October 2017

Richard Kay

8

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Europe PubMed Central

PubMed publication ID

19 October 2017

Zvi Ram

9

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Europe PubMed Central

PubMed publication ID

19 October 2017

ASPECT Study Group

10

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Europe PubMed Central

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19 October 2017

publication date

12 July 2013

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Europe PubMed Central

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19 October 2017

Lancet Oncology Commission

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Europe PubMed Central

PubMed publication ID

19 October 2017

14

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Europe PubMed Central

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19 October 2017

9

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Europe PubMed Central

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19 October 2017

823-833

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Europe PubMed Central

PubMed publication ID

19 October 2017

Malignant gliomas in adults

1 reference

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Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias

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An extent of resection threshold for newly diagnosed glioblastomas

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

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Cost of Migration: Invasion of Malignant Gliomas and Implications for Treatment

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A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma

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A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

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In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy

1 reference

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Gap junction-mediated bystander effect in primary cultures of human malignant gliomas with recombinant expression of the HSVtk gene

1 reference

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Preferential transduction of neurons by canine adenovirus vectors and their efficient retrograde transport in vivo

1 reference

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Adenovirus binding to the coxsackievirus and adenovirus receptor or integrins is not required to elicit brain inflammation but is necessary to transduce specific neural cell types

1 reference

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Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

1 reference

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Beta-galactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses

1 reference

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AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study

1 reference

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A preclinical assessment of the safety and biodistribution of an adenoviral vector containing the herpes simplex virus thymidine kinase gene (Cerepro) after intracerebral administration

1 reference

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Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma.

1 reference

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Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas

1 reference

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7 January 2021

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Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas.

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Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol

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Monotherapy trials: sequential design

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MGMT gene silencing and benefit from temozolomide in glioblastoma

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7 January 2021

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Effects of covariate omission and categorization when analysing randomized trials with the Cox model

1 reference

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7 January 2021

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Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells

1 reference

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7 January 2021

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Gene therapy for malignant glioma: current clinical status

1 reference

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7 January 2021

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Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3.

1 reference

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Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial.

1 reference

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7 January 2021

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Application of novel response/progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) Working Group

1 reference

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End point assessment in gliomas: novel treatments limit usefulness of classical Macdonald's Criteria

1 reference

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Local inflammation and devascularization--in vivo mechanisms of the "bystander effect" in VPC-mediated HSV-Tk/GCV gene therapy for human malignant glioma

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Introduction to the background, principles, and state of the art in suicide gene therapy.

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Mechanisms of local immunoresistance in glioma

1 reference

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Current status of gene therapy for brain tumors.

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inferred from DOI database lookup

Identifiers

10.1016/S1470-2045(13)70274-2

1 reference

Europe PubMed Central

PubMed publication ID

19 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 October 2017

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