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English
Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment
scientific article published on November 2005
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
title
Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
main subject
progeria
1 reference
based on heuristic
inferred from title
author
Giuseppe Novelli
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
Marta Columbaro
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
Cristina Capanni
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
Elisabetta Mattioli
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
Stefano Squarzoni
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
Giovanna Lattanzi
series ordinal
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
author name string
V K Parnaik
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
N M Maraldi
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
publication date
1 November 2005
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
published in
Cellular and Molecular Life Sciences
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
volume
62
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
issue
22
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
page(s)
2669-2678
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
cites work
Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes
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PubMed Central
reference URL
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5 June 2018
Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome
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PubMed Central
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5 June 2018
Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition
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PubMed Central
reference URL
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5 June 2018
Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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Genomic instability in laminopathy-based premature aging
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Altered pre-lamin A processing is a common mechanism leading to lipodystrophy.
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Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
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5 June 2018
Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice
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5 June 2018
Laminopathies: involvement of structural nuclear proteins in the pathogenesis of an increasing number of human diseases
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5 June 2018
Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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5 June 2018
Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains
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Zinc metalloproteinase, ZMPSTE24, is mutated in mandibuloacral dysplasia
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LMNA is mutated in Hutchinson-Gilford progeria (MIM 176670) but not in Wiedemann-Rautenstrauch progeroid syndrome (MIM 264090).
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5 June 2018
Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
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5 June 2018
Lamin a truncation in Hutchinson-Gilford progeria.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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5 June 2018
Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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5 June 2018
Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect.
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PubMed Central
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5 June 2018
Experimental condensation inhibition in constitutive and facultative heterochromatin of mammalian chromosomes
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5 June 2018
Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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5 June 2018
Lamin A precursor is localized to intranuclear foci.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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5 June 2018
A new staining procedure for electron microscopical cytology.
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PubMed Central
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5 June 2018
Alterations of nuclear envelope and chromatin organization in mandibuloacral dysplasia, a rare form of laminopathy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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17 August 2018
Novel lamin A/C gene (LMNA) mutations in atypical progeroid syndromes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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17 August 2018
Paternal origin of LMNA mutations in Hutchinson-Gilford progeria
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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17 August 2018
Failure of lamin A/C to functionally assemble in R482L mutated familial partial lipodystrophy fibroblasts: altered intermolecular interaction with emerin and implications for gene transcription
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17 August 2018
The carboxyl-terminal region common to lamins A and C contains a DNA binding domain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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17 August 2018
Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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17 August 2018
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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17 August 2018
Nuclear alterations in autosomal-dominant Emery-Dreifuss muscular dystrophy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
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3 November 2018
Nuclear changes in a case of X-linked Emery-Dreifuss muscular dystrophy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2773834
retrieved
3 November 2018
Identifiers
DOI
10.1007/S00018-005-5318-6
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
PMC publication ID
2773834
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
PubMed publication ID
16261260
1 reference
stated in
Europe PubMed Central
PMC publication ID
2773834
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16261260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
ResearchGate publication ID
7506310
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