(Q42056708)

15 October 2017

iRHOM2 is a critical pathogenic mediator of inflammatory arthritis (English)

1 reference

15 October 2017

0 references

Lionel B Ivashkiv

1 reference

15 October 2017

George D Kalliolias

1 reference

15 October 2017

Priya Darshinee A Issuree

1 reference

15 October 2017

Thorsten Maretzky

1 reference

15 October 2017

David R McIlwain

1 reference

15 October 2017

Sébastien Monette

1 reference

15 October 2017

Xiaoping Qing

1 reference

15 October 2017

Philipp A Lang

1 reference

15 October 2017

Steven L Swendeman

1 reference

15 October 2017

Kyung-Hyun Park-Min

1 reference

15 October 2017

Nikolaus Binder

1 reference

15 October 2017

Anna Yarilina

1 reference

15 October 2017

Keisuke Horiuchi

1 reference

15 October 2017

Tak W Mak

1 reference

15 October 2017

Jane E Salmon

1 reference

15 October 2017

Carl P Blobel

1 reference

15 October 2017

language of work or name

English

0 references

publication date

25 January 2013

1 reference

Journal of Clinical Investigation

15 October 2017

1 reference

15 October 2017

123

1 reference

15 October 2017

1 reference

15 October 2017

928-932

1 reference

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

iRhom2 is required for the secretion of mouse TNFα

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Cross-domain inhibition of TACE ectodomain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Intravenous immunoglobulins--understanding properties and mechanisms

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

ADAMs: key components in EGFR signalling and development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Interleukin 1 receptor dependence of serum transferred arthritis can be circumvented by toll-like receptor 4 signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Impaired Inflammatory Responses in the Reverse Arthus Reaction Through Genetic Deletion of the C5a Receptor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Inflammatory skin and bowel disease linked to ADAM17 deletion

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Arthritis critically dependent on innate immune system players

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561822

Marrow Stromal Cells and Osteoclast Precursors Differentially Contribute to TNF- -Induced Osteoclastogenesis In Vivo

17 August 2018

1 reference

12 December 2020

An essential role for ectodomain shedding in mammalian development

1 reference

12 December 2020

Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock

1 reference

12 December 2020

Sensitization of IFN-γ Jak-STAT signaling during macrophage activation

1 reference

12 December 2020

A codominant role of Fc gamma RI/III and C5aR in the reverse Arthus reaction

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI66168

1 reference

15 October 2017

1 reference

15 October 2017

PubMed publication ID

23348744

1 reference