(Q41840813)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Sheena M Whyte

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Ian D Sylvester

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Stephen R Martin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Franziska Wopfner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Guy G Dodson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Peter M Bayley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

0 references

publication date

1 July 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

373

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

Pt 2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

485-494

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

NMR structure of a variant human prion protein with two disulfide bridges

2 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Prion and doppel proteins bind to granule cells of the cerebellum

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

The human "prion-like" protein Doppel is expressed in both Sertoli cells and spermatozoa

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Absence of the prion protein homologue Doppel causes male sterility

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Protein Structure and the Energetics of Protein Stability.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Doppel-induced cerebellar degeneration in transgenic mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

PrPC directly interacts with proteins involved in signaling pathways

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Two different neurodegenerative diseases caused by proteins with similar structures

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Expression and structural characterization of the recombinant human doppel protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Signal transduction through prion protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Ligand binding and thermodynamic stability of a multidomain protein, calmodulin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

NMR structure of the bovine prion protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

First report of polymorphisms in the prion-like protein gene (PRND): implications for human prion diseases

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Aggregation and fibrillization of the recombinant human prion protein huPrP90-231.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

NMR solution structure of the human prion protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Prion protein interconversions and the transmissible spongiform encephalopathies

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

A scrapie-like unfolding intermediate of the prion protein domain PrP(121-231) induced by acidic pH.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

6 June 2018

Prion Protein Biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

The cellular prion protein binds copper in vivo

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Deadly conformations--protein misfolding in prion disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Target recognition by calmodulin: dissecting the kinetics and affinity of interaction using short peptide sequences

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

NMR structure of the mouse prion protein domain PrP(121-231)

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

The Ninth Datta Lecture. Molecular biology of transmissible spongiform encephalopathies

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Denaturant m values and heat capacity changes: relation to changes in accessible surface areas of protein unfolding

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Thermal stability and conformational transitions of scrapie amyloid (prion) protein correlate with infectivity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Determination and analysis of urea and guanidine hydrochloride denaturation curves

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

6 June 2018

Protein stability curves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Calculation of protein extinction coefficients from amino acid sequence data

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Equilibrium and kinetics of the thermal unfolding of α-lactalbumin. The relation to its folding mechanism

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

A cluster of familial Creutzfeldt-Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Amyloidogenic unfolding intermediates differentiate sheep prion protein variants

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Folding and intrinsic stability of deletion variants of PrP(121-231), the folded C-terminal domain of the prion protein

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Expression of doppel in the CNS of mice does not modulate transmissible spongiform encephalopathy disease

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

On the mechanism of alpha-helix to beta-sheet transition in the recombinant prion protein.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Folding of prion protein to its native alpha-helical conformation is under kinetic control

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Inhibition of interactions and interconversions of prion protein isoforms by peptide fragments from the C-terminal folded domain.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Astrocytic glutamate uptake and prion protein expression

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Familial mutations and the thermodynamic stability of the recombinant human prion protein

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Neurotoxicity of a prion protein fragment

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Conformational transitions in peptides containing two putative alpha-helices of the prion protein.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

The cellular prion protein binds copper in vivo

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223489

Doppel and PrPCdo not share the same membrane microenvironment

30 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12665426

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

pH-dependent stability and conformation of the recombinant human prion protein PrP(90-231)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12665426

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20021911

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

12665426

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12665426%20AND%20SRC:MED&resulttype=core&format=json