(Q41730130)

8 October 2017

title

Clarifying the catalytic roles of conserved residues in the amidase signature family (English)

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8 October 2017

M P Patricelli

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8 October 2017

B F Cravatt

series ordinal

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8 October 2017

language of work or name

English

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publication date

1 June 2000

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Journal of Biological Chemistry

8 October 2017

published in

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8 October 2017

volume

275

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8 October 2017

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8 October 2017

page(s)

19177-19184

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Purification, cloning, and primary structure of an enantiomer-selective amidase from Brevibacterium sp. strain R312: structural evidence for genetic coupling with nitrile hydratase

8 October 2017

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Amidase coupled with low-molecular-mass nitrile hydratase from Rhodococcus rhodochrous J1. Sequencing and expression of the gene and purification and characterization of the gene product

21 January 2018

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Cloning and characterization of an amidase gene from Rhodococcus species N-774 and its expression in Escherichia coli

21 January 2018

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Cloning and molecular characterization of the acetamidase-encoding gene (amdS) from Aspergillus oryzae

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Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

21 January 2018

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Studies on the role of the areA gene in the regulation of nitrogen catabolism in Aspergillus nidulans

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Glu-tRNAGln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation

21 January 2018

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Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: identification of the transmembrane domain as a site for oligomerization

21 January 2018

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Chemical and mutagenic investigations of fatty acid amide hydrolase: evidence for a family of serine hydrolases with distinct catalytic properties

21 January 2018

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Fatty acid amide hydrolase competitively degrades bioactive amides and esters through a nonconventional catalytic mechanism

21 January 2018

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Isolation and structure of a brain constituent that binds to the cannabinoid receptor

21 January 2018

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Chemical characterization of a family of brain lipids that induce sleep

21 January 2018

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Cerebrodiene: a brain lipid isolated from sleep-deprived cats

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Characterization of the hypnotic properties of oleamide

21 January 2018

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The hypnotic actions of oleamide are blocked by a cannabinoid receptor antagonist

21 January 2018

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21 January 2018

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The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain

21 January 2018

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21 January 2018

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Catalytic triads and their relatives

21 January 2018

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Identification of active sites in amidase: Evolutionary relationship between amide bond- and peptide bond-cleaving enzymes

21 January 2018

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Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

21 January 2018

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21 January 2018

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Molecular characterization of human and mouse fatty acid amide hydrolases

21 January 2018

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21 January 2018

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Functional characteristics of the oxyanion hole in human acetylcholinesterase

21 January 2018

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Anandamide amidohydrolase of porcine brain: cDNA cloning, functional expression and site-directed mutagenesis(1).

21 January 2018

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Dissecting the catalytic triad of a serine protease

21 January 2018

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Studies on the hydrolytic properties of (serine) carboxypeptidase Y.

21 January 2018

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Functional interaction among catalytic residues in subtilisin BPN'.

21 January 2018

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Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist

21 January 2018

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Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

21 January 2018

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2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

21 January 2018

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Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor

21 January 2018

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The chemistry and enzymology of the type I signal peptidases

21 January 2018

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Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

21 January 2018

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Structure of the UmuD' protein and its regulation in response to DNA damage

21 January 2018

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Crystal structure of human cytosolic phospholipase A2 reveals a novel topology and catalytic mechanism

21 January 2018

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Study of the amidase signature group

21 January 2018

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The vitamin D3 hydroxylase-associated protein is a propionamide-metabolizing amidase enzyme

21 January 2018

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Extrapyramidal effects of methanandamide, an analog of anandamide, the endogenous CB1 receptor ligand

21 January 2018

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The catalytic role of the active site aspartic acid in serine proteases

21 January 2018

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The architecture of human acetylcholinesterase active center probed by interactions with selected organophosphate inhibitors

21 January 2018

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Oligopeptidase B: a new type of serine peptidase with a unique substrate-dependent temperature sensitivity

21 January 2018

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Identification of two serine residues involved in catalysis by fatty acid amide hydrolase

21 January 2018

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Engineering enzyme specificity by "substrate-assisted catalysis"

21 January 2018

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Site-directed mutagenesis on (serine) carboxypeptidase Y. A hydrogen bond network stabilizes the transition state by interaction with the C-terminal carboxylate group of the substrate

21 January 2018

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Rational design of alpha-keto triglyceride analogues as inhibitors for Staphylococcus hyicus lipase

21 January 2018

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Autodigestion and RecA-dependent cleavage of Ind- mutant LexA proteins

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M001607200

1 reference

8 October 2017

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