(Q41610270)

English

Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: prediction of in vivo drug interactions

scientific article published on March 2000

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: prediction of in vivo drug interactions (English)

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

1 reference

based on heuristic

inferred from title

Hiroshi Yamazaki

5

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

author name string

K Ohyama

1

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

M Nakajima

2

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

M Suzuki

3

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

N Shimada

4

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

T Yokoi

6

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

language of work or name

0 references

publication date

1 March 2000

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

49

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

3

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

244-253

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

Molecular genetics of the human cytochrome P450 monooxygenase superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Involvement of CYP1A2 in mexiletine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

(R)-(+)-Menthofuran is a potent, mechanism-based inactivator of human liver cytochrome P450 2A6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Inhibitory effects of antiarrhythmic drugs on phenacetin O-deethylation catalysed by human CYP1A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Adverse effects of amiodarone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2000.00134.X

21 January 2018

Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo data.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Amiodarone N-deethylation in human liver microsomes: involvement of cytochrome P450 3A enzymes (first report).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Relationships between amiodarone dosage, drug concentrations, and adverse side effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Clinical pharmacokinetics of amiodarone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Amiodarone and desethylamiodarone elimination kinetics following withdrawal of long-term amiodarone maintenance therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Pharmacokinetic interactions of cimetidine 1987.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Amiodarone-cyclosporine interaction in a heart transplant patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Amiodarone. An overview of its pharmacological properties, and review of its therapeutic use in cardiac arrhythmias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

6 June 2018

Potent and selective inactivation of human liver microsomal cytochrome P-450 isoforms by L-754,394, an investigational human immune deficiency virus protease inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014912

19 August 2018

Influence of amiodarone on genetically determined drug metabolism in humans

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2000.00134.X

21 January 2018

Effects of erythromycin on hepatic drug-metabolizing enzymes in humans

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2000.00134.X

21 January 2018

Highly sensitive high-performance liquid chromatographic assay for coumarin 7-hydroxylation and 7-ethoxycoumarin O-deethylation by human liver cytochrome P450 enzymes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2000.00134.X

21 January 2018

Serum concentrations of amiodarone during long term therapy. Relation to dose, efficacy and toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporine-amiodarone interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform-selective mechanism-based inhibition of human cytochrome P450 1A2 by furafylline

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variable disposition kinetics and electrocardiographic effects of flecainide during repeated dosing in humans: contribution of genetic factors, dose-dependent clearance, and interaction with amiodarone

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibitory effect of amiodarone and desethylamiodarone on dextromethorphan O-demethylation in human and rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly sensitive and specific high-performance liquid chromatographic analysis of 7-hydroxywarfarin, a marker for human cytochrome P-4502C9 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biotransformation of chlorzoxazone by hepatic microsomes from humans and ten other mammalian species

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amiodarone kinetics after oral doses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of amiodarone by serum proteins and the effects of drugs, hormones and other interacting ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of amiodarone, desethylamiodarone and other iodine-containing amiodarone metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of an inactive cytochrome P-450Fe(II)-metabolite complex after administration of amiodarone in rats, mice and hamsters

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of amiodarone with racemic warfarin and its separated enantiomorphs in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction between intravenous phenytoin and amiodarone in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

43 Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of the interaction between amiodarone and warfarin in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of amiodarone after intravenous and oral administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of clarithromycin and its metabolites on the mixed function oxidase system in hepatic microsomes of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amiodarone pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/10718780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2125.2000.00134.X

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 October 2017

ResearchGate publication ID

0 references

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