(Q41392084)

30 September 2017

title

Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis (English)

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30 September 2017

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30 September 2017

Hongtan Wu

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30 September 2017

Luyao Wei

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30 September 2017

Fuqin Fan

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30 September 2017

Suyuan Ji

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30 September 2017

Shihao Zhang

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30 September 2017

Jing Geng

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30 September 2017

Lixin Hong

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30 September 2017

Xin Fan

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30 September 2017

Qinghua Chen

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30 September 2017

Jing Tian

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30 September 2017

Mingting Jiang

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30 September 2017

Xiufeng Sun

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30 September 2017

Changnan Jin

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30 September 2017

Zhen-Yu Yin

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30 September 2017

Qingxu Liu

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30 September 2017

Jinjia Zhang

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30 September 2017

Funiu Qin

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30 September 2017

Kwang-Huei Lin

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30 September 2017

Jau-Song Yu

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30 September 2017

Xianming Deng

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30 September 2017

Hong-Rui Wang

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30 September 2017

Bin Zhao

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30 September 2017

Randy L Johnson

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30 September 2017

Lanfen Chen

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30 September 2017

language of work or name

English

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publication date

19 February 2015

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30 September 2017

published in

Nature Communications

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30 September 2017

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30 September 2017

page(s)

6239

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The unfolded protein response: from stress pathway to homeostatic regulation

30 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The impact of the unfolded protein response on human disease

21 January 2018

1 reference

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Translational control in stress and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7239

Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

XBP1: the last two decades

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7239

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The Hippo pathway and human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7239

Structures of YAP protein domains reveal promising targets for development of new cancer drugs

21 January 2018

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The Hippo Signaling Pathway in Development and Cancer

21 January 2018

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PP1A-mediated dephosphorylation positively regulates YAP2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7239

Contact-dependent inhibition of EGFR signaling by Nf2/Merlin

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS7239

The Hippo pathway regulates Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Role of TAZ as mediator of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Elucidation of a universal size-control mechanism in Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

YAP1 increases organ size and expands undifferentiated progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Yap1 acts downstream of α-catenin to control epidermal proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Ablation of the kinase NDR1 predisposes mice to the development of T cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The YAP and TAZ transcription co-activators: key downstream effectors of the mammalian Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Targeting the unfolded protein response in disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

TEAD mediates YAP-dependent gene induction and growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Control of cellular GADD34 levels by the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Association with endoplasmic reticulum promotes proteasomal degradation of GADD34 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Endoplasmic reticulum stress in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

ER stress, hypoxia tolerance and tumor progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

IRE1 signaling affects cell fate during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7239

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS7239

1 reference

release_y3kqo4yvozetpdrh5ja7uavzum

30 September 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/y3kqo4yvozetpdrh5ja7uavzum

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference