(Q41125972)

27 September 2017

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title

Inhibition of signaling from Type 1 receptor tyrosine kinases via intracellular expression of single-chain antibodies (English)

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27 September 2017

R R Beerli

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27 September 2017

W Wels

series ordinal

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27 September 2017

N E Hynes

series ordinal

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27 September 2017

language of work or name

English

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publication date

1 January 1996

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Breast Cancer Research and Treatment

27 September 2017

published in

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27 September 2017

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27 September 2017

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27 September 2017

page(s)

11-17

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p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

27 September 2017

cites work

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https://api.crossref.org/works/10.1007%2FBF01803779

Monoclonal antibodies directed to the erbB-2 receptor inhibit in vivo tumour cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01803779

Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01803779

ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01803779

Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01803779

Neu and its ligands: from an oncogene to neural factors

21 January 2018

1 reference

12 December 2020

Autocrine inhibition of the epidermal growth factor receptor by intracellular expression of a single-chain antibody

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12 December 2020

EGF receptor and p185erbB-2-specific single-chain antibody toxins differ in their cell-killing activity on tumor cells expressing both receptor proteins

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12 December 2020

Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers

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12 December 2020

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli

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12 December 2020

Intracellular expression of single chain antibodies reverts ErbB-2 transformation.

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12 December 2020

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

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12 December 2020

Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation

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12 December 2020

RETRACTED: 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity

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12 December 2020

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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12 December 2020

p185c-erbB-2 signal enhances cisplatin-induced cytotoxicity in human breast carcinoma cells: association between an oncogenic receptor tyrosine kinase and drug-induced DNA repair.

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12 December 2020

Monoclonal antibodies against the extracellular domain of the erbB-2 receptor function as partial ligand agonists

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12 December 2020

A C-terminal signal prevents secretion of luminal ER proteins

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12 December 2020

Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies.

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12 December 2020

Recombinant anti-erbB2 immunotoxins containing Pseudomonas exotoxin

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12 December 2020

Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.

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12 December 2020

Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells

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12 December 2020

Amphiregulin induces tyrosine phosphorylation of the epidermal growth factor receptor and p185erbB2. Evidence that amphiregulin acts exclusively through the epidermal growth factor receptor at the surface of human epithelial cells

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12 December 2020

Cloning immunoglobulin variable domains for expression by the polymerase chain reaction

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12 December 2020

Stimulation of pp60c-src kinase activity in FDC-P1 cells by polyoma middle-T antigen and hematopoietic growth factors

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12 December 2020

Antitumor activity of a transforming growth factor alpha-Pseudomonas exotoxin fusion protein (TGF-alpha-PE40).

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12 December 2020

Single-chain antigen-binding proteins

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12 December 2020

Construction, bacterial expression and characterization of a bifunctional single-chain antibody-phosphatase fusion protein targeted to the human erbB-2 receptor

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12 December 2020

Cytotoxic T lymphocytes with a grafted recognition specificity for ERBB2-expressing tumor cells

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12 December 2020

Amplification and overexpression of the erbB-2 gene in human tumors: its involvement in tumor development, significance as a prognostic factor, and potential as a target for cancer therapy.

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12 December 2020

Selective inhibition of tumor cell growth by a recombinant single-chain antibody-toxin specific for the erbB-2 receptor

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12 December 2020

Mechanistic aspects of the opposing effects of monoclonal antibodies to the ERBB2 receptor on tumor growth

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12 December 2020

Identifiers

DOI

10.1007/BF01803779

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Dimensions Publication ID

27 September 2017

1026012826

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