(Q41018716)

25 September 2017

3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping (English)

1 reference

25 September 2017

Jorge Z Torres

0 references

Yu-Chen Lo

1 reference

25 September 2017

Silvia Senese

series ordinal

1 reference

25 September 2017

Robert Damoiseaux

series ordinal

1 reference

25 September 2017

10 June 2016

1 reference

25 September 2017

1 reference

25 September 2017

1 reference

25 September 2017

1 reference

25 September 2017

2244-2253

1 reference

describes a project that uses

25 September 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

cites work

Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Comparison of ultra-fast 2D and 3D ligand and target descriptors for side effect prediction and network analysis in polypharmacology.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Target identification and mechanism of action in chemical biology and drug discovery

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

HIV-1 NNRTIs: structural diversity, pharmacophore similarity, and implications for drug design

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Small-molecule inducers of insulin expression in pancreatic alpha-cells.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Optimal assignment methods for ligand-based virtual screening

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Network-based prediction of protein function

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Relating protein pharmacology by ligand chemistry

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Benchmarking sets for molecular docking

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Small molecule shape-fingerprints

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Chemical proteomics applied to target identification and drug discovery

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

The taxol pharmacophore and the T-taxol bridging principle.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Refined structure of alpha beta-tubulin at 3.5 A resolution

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Taxol (paclitaxel): mechanisms of action

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Structure-based strategies for drug design and discovery

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Genomic profiling of drug sensitivities via induced haploinsufficiency.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Enhancing molecular shape comparison by weighted Gaussian functions

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Exploring polypharmacology using a ROCS-based target fishing approach

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Pharao: pharmacophore alignment and optimization

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

Enhanced solubility of paclitaxel using water‐soluble and biocompatible 2‐methacryloyloxyethyl phosphorylcholine polymers

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5511031

GS-164, a small synthetic compound, stimulates tubulin polymerization by a similar mechanism to that of Taxol

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27285961

12 December 2020

inferred from PubMed ID database lookup

PASS: prediction of activity spectra for biologically active substances

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27285961

12 December 2020

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/27285961

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1021/ACSCHEMBIO.6B00253

1 reference

25 September 2017

1 reference

25 September 2017

PubMed publication ID

27285961

1 reference