(Q41015843)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

title

Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Xiaobo Mao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Michael Tianhao Ou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Xiling Yin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Yulan Xiong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

George Essien Umanah

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Saurav Brahmachari

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Joo-Ho Shin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Ho Chul Kang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Jianmin Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Jinchong Xu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Rong Chen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Hyejin Park

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Shaida A Andrabi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Sung Ung Kang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Rafaella Araújo Gonçalves

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Shu Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Chen Qi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Sharon Lam

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

James A Keiler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Joel Tyson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Donghoon Kim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Seung Pil Yun

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Creg J Workman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Dario A A Vignali

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Valina L Dawson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Han Seok Ko

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Senthilkumar S Karuppagounder

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Ted M Dawson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

language of work or name

English

0 references

publication date

1 September 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

volume

353

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

issue

6307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

25 March 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5510615/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5510615/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Ca2+ is a key factor in α-synuclein-induced neurotoxicity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Mesenchymal Stem Cells Inhibit Transmission of α-Synuclein by Modulating Clathrin-Mediated Endocytosis in a Parkinsonian Model

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Review: Sporadic Parkinson's disease: development and distribution of α-synuclein pathology

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Sorting out release, uptake and processing of alpha-synuclein during prion-like spread of pathology

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Alpha-synuclein propagation: New insights from animal models

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

α-synuclein assemblies sequester neuronal α3-Na+/K+-ATPase and impair Na+ gradient

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Neurodegenerative diseases: expanding the prion concept

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

The c-Abl inhibitor, nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

α-Synuclein promotes clathrin-mediated NMDA receptor endocytosis and attenuates NMDA-induced dopaminergic cell death

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Raised calcium promotes α-synuclein aggregate formation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Behavioral phenotyping of mouse models of Parkinson's disease

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

alpha-Synuclein modulation of Ca2+ signaling in human neuroblastoma (SH-SY5Y) cells

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Fluorescent indicators for intracellular pH.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Alpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recycling

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Staging of brain pathology related to sporadic Parkinson's disease

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3).

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Control of glial immune function by neurons

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Alpha-synuclein and neurodegenerative diseases

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Functional requirement for class I MHC in CNS development and plasticity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Cloning and characterization of RTK ligands using receptor-alkaline phosphatase fusion proteins

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Characterization of the major histocompatibility complex class II binding site on LAG-3 protein

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Independent modes of natural killing distinguished in mice lacking Lag3

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Cell-to-cell transmission of α-synuclein aggregates

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Inhibition of adenylyl cyclase type 5 prevents L-DOPA-induced dyskinesia in an animal model of Parkinson's disease.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Deregulation of calcium homeostasis mediates secreted α-synuclein-induced neurotoxicity

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

100 years of Lewy pathology

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

MHC class I: an unexpected role in neuronal plasticity

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5510615

19 August 2018

Identifiers

DOI

10.1126/SCIENCE.AAH3374

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

PubMed publication ID

27708076

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27708076%20AND%20SRC:MED&resulttype=core&format=json