(Q40923059)

24 September 2017

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title

Gender effects in pharmacokinetics and pharmacodynamics (English)

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24 September 2017

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R Z Harris

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24 September 2017

L Z Benet

series ordinal

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24 September 2017

J B Schwartz

series ordinal

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24 September 2017

language of work or name

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1 August 1995

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24 September 2017

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24 September 2017

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24 September 2017

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24 September 2017

page(s)

222-239

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Effect of age and gender on disposition of temazepam

24 September 2017

cites work

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12 December 2020

Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes

1 reference

12 December 2020

Effects of age and gender on pharmacokinetics of cefepime

1 reference

12 December 2020

Neuroendocrine effects of M-chlorophenylpiperazine, a serotonin agonist, in humans

1 reference

12 December 2020

Human gastric alcohol dehydrogenase activity: effect of age, sex, and alcoholism

1 reference

12 December 2020

Influence of sex and oral contraceptive steroids on paracetamol metabolism

1 reference

12 December 2020

Starch malabsorption and stool excretion are influenced by the menstrual cycle in women consuming low-fibre Western diets

1 reference

12 December 2020

Hypertension in women: what is really known? The Women's Caucus, Working Group on Women's Health of the Society of General Internal Medicine

1 reference

12 December 2020

Supplemental estrogen replacement.

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12 December 2020

1 reference

12 December 2020

Pharmacokinetics of pravastatin in elderly versus young men and women

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12 December 2020

Disposition of cefotaxime and its desacetyl metabolite in morbidly obese male and female subjects.

1 reference

12 December 2020

Relative importance of dose, body surface area, sex, and age for 5-fluorouracil clearance

1 reference

12 December 2020

Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II

1 reference

12 December 2020

Thiothixene pharmacokinetic interactions: a study of hepatic enzyme inducers, clearance inhibitors, and demographic variables

1 reference

12 December 2020

Piroxicam and naproxen plasma concentrations in patients with osteoarthritis: relation to age, sex, efficacy and adverse events

1 reference

12 December 2020

Postmenopausal hormone replacement therapy and cardiovascular risk reduction. A review.

1 reference

12 December 2020

Impairment of prednisolone disposition in women taking oral contraceptives or conjugated estrogens.

1 reference

12 December 2020

The pharmacokinetics and safety of zidovudine in the third trimester of pregnancy for women infected with human immunodeficiency virus and their infants: phase I acquired immunodeficiency syndrome clinical trials group study (protocol 082). Zidovudi

1 reference

12 December 2020

Pathway-selective sex differences in the metabolic clearance of propranolol in human subjects

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12 December 2020

Forms of atypical depression and their response to antidepressant drugs

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12 December 2020

Coronary disease: are there gender differences?

1 reference

12 December 2020

Comparative pharmacokinetics of paracetamol in men and women considering follicular and luteal phases

1 reference

12 December 2020

Gender differences in pharmacokinetics and pharmacodynamics of psychotropic medication

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12 December 2020

Pharmacokinetics of sufentanil in obese patients

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12 December 2020

Racial and gender differences in N-acetyltransferase, xanthine oxidase, and CYP1A2 activities

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12 December 2020

Progestin replacement in the menopause: effects on the endometrium and serum lipids.

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12 December 2020

Identification of an inducible form of cytochrome P-450 in human liver

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12 December 2020

Frequency distribution of dapsone N-hydroxylase, a putative probe for P4503A4 activity, in a white population

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12 December 2020

Trazodone kinetics: effect of age, gender, and obesity

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12 December 2020

Effects of age and sex on copper absorption, biological half-life, and status in humans

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12 December 2020

Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

Influence of oral contraceptives on drug therapy

1 reference

12 December 2020

Sex differences in absorption kinetics of sodium salicylate

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12 December 2020

Obesity, sex, and acetaminophen disposition

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12 December 2020

Phenytoin pharmacokinetics in catamenial epilepsy

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12 December 2020

Gender and age as factors in the inhibition of renal clearance of amantadine by quinine and quinidine

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12 December 2020

Influence of sex and age on fluorouracil clearance

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12 December 2020

Application of a three-compartment model to a study of the effects of sex, alcohol dose and concentration, exercise and food consumption on the pharmacokinetics of ethanol in healthy volunteers

1 reference

12 December 2020

Seasonal variations in binding of 3H-paroxetine to blood platelets in healthy volunteers: indications for a gender difference

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12 December 2020

Bromazepam pharmacokinetics: influence of age, gender, oral contraceptives, cimetidine, and propranolol

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12 December 2020

Alcohol effects in women during the menstrual cycle

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12 December 2020

Effect of age, gender, and obesity on midazolam kinetics.

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12 December 2020

Oral contraceptive drug interactions: important considerations

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12 December 2020

Self-catalyzed inactivation of hepatic cytochrome P-450 by ethynyl substrates

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12 December 2020

Pimozide in the treatment of newly admitted schizophrenic patients

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12 December 2020

Oxazepam kinetics: effects of age and sex.

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12 December 2020

The effect of sex and cardiac failure on the pharmacokinetics of a slow-release theophylline formulation in the elderly

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12 December 2020

Pregnancy-induced changes in drug metabolism in epileptic women

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12 December 2020

Imipramine and desipramine disposition in the elderly

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12 December 2020

Influence of menstrual cycle and gender on alprazolam pharmacokinetics

1 reference

12 December 2020

Anticonvulsants in pregnancy

1 reference

12 December 2020

Effect of age and gender on the activity of human hepatic CYP3A

1 reference

12 December 2020

Diazepam Kinetics in Relation to Age and Sex

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12 December 2020

Influence of age on the pharmacokinetics of alfentanil. Gender dependence

1 reference

12 December 2020

Intersubject and dose-related variability after intravenous administration of erythromycin.

1 reference

12 December 2020

Hepatic drug metabolism and aging

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12 December 2020

Clinical pharmacokinetics of drugs in obesity. An update

1 reference

12 December 2020

Effect of age and sex on glomerular filtration rate measured by 51Cr-EDTA

1 reference

12 December 2020

Effects of age and gender on in vitro properties of human liver microsomal monooxygenases

1 reference

12 December 2020

Antipyrine metabolism during the menstrual cycle

1 reference

12 December 2020

Sex-specific cytochrome P450 as a cause of sex- and species-related differences in drug toxicity

1 reference

12 December 2020

Factors affecting the enterohepatic circulation of oral contraceptive steroids

1 reference

12 December 2020

Propranolol metabolism in normal subjects: association with sex steroid hormones

1 reference

12 December 2020

Aging of women alters S-verapamil pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

The pharmacokinetics of ondansetron after intravenous injection in healthy volunteers phenotyped as poor or extensive metabolisers of debrisoquine

1 reference

12 December 2020

Evidence for estrogen receptor-linked calcium transport in the intestine

1 reference

12 December 2020

The human hepatic cytochromes P450 involved in drug metabolism

1 reference

12 December 2020

Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms.

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12 December 2020

Blood flow in muscle groups and drug absorption

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12 December 2020

Age and gender influence the stereoselective pharmacokinetics of propranolol

1 reference

12 December 2020

Age-dependent cyclosporine: pharmacokinetics in marrow transplant recipients

1 reference

12 December 2020

A major role for cytochrome P450TB (CYP2C subfamily) in the actions of non-steroidal antiinflammatory drugs

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12 December 2020

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12 December 2020

Alterations in prednisolone disposition as a result of time of administration, gender and dose

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12 December 2020

N-demethylation of ethylmorphine in pregnant and non-pregnant women and in men: an evaluation of the effects of sex steroids

1 reference

12 December 2020

Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation

1 reference

12 December 2020

The polymorphic cytochrome P-4502D6 is involved in the metabolism of both 5-hydroxytryptamine antagonists, tropisetron and ondansetron

1 reference

12 December 2020

Differences in men and women in coronary artery disease, systemic hypertension and their treatment

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12 December 2020

Effect of age, gender and anaesthetic technique on the pharmacodynamics of atracurium

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12 December 2020

Sex-difference and the effects of smoking and oral contraceptive steroids on the kinetics of diflunisal

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12 December 2020

Inhibition of oral contraceptive steroid-metabolizing enzymes by steroids and drugs

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12 December 2020

Pharmacokinetic Drug Interactions with Oral Contraceptives

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12 December 2020

Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity

1 reference

12 December 2020

Plasma antiepileptic drug concentrations during pregnancy

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12 December 2020

Effects of age, gender and oral contraceptives on intramuscular midazolam pharmacokinetics

1 reference

12 December 2020

Age and gender effects on ondansetron pharmacokinetics: evaluation of healthy aged volunteers

1 reference

12 December 2020

A controlled clinical trial of fluspirilene, a long-acting injectable neuroleptic, in schizophrenic patients with acute exacerbation

1 reference

12 December 2020

Estimating the Dosage of Ribavirin Aerosol According to Age and Other Variables

1 reference

12 December 2020

Cytochrome P450 mediated metabolism of diazepam in human and rat: involvement of human CYP2C in N-demethylation in the substrate concentration-dependent manner

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12 December 2020

Sex, age and alfentanil pharmacokinetics

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12 December 2020

Rifampin, oral contraceptives, and pregnancy

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12 December 2020

Effect of age and sex on lorazepam protein binding

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12 December 2020

Menstrual cycle effects on caffeine elimination in the human female

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12 December 2020

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

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12 December 2020

Disposition of carbamazepine and phenytoin in pregnancy

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12 December 2020

Estrogen inhibits the dopaminergic supersensitivity induced by neuroleptics

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12 December 2020

Effect of age and sex on the plasma binding of acidic and basic drugs

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12 December 2020

The intra- and inter-subject variability of nifedipine pharmacokinetics in young volunteers

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12 December 2020

Clinical trials and transethnic pharmacology

1 reference

12 December 2020

Pharmacokinetic study of RU 486 and its metabolites after oral administration of single doses to pregnant and non-pregnant women

1 reference

12 December 2020

Digoxin population pharmacokinetics from routine clinical data: role of patient characteristics for estimating dosing regimens

1 reference

12 December 2020

Interactions with oral contraceptives

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12 December 2020

Hormone replacement therapy for prevention and treatment of osteoporosis

1 reference

12 December 2020

Pharmacokinetics of anticonvulsants in pregnancy: alterations in plasma protein binding

1 reference

12 December 2020

Inter- and intrasubject variation in diazepam free fraction

1 reference

12 December 2020

Aging and alfentanil disposition in healthy volunteers and surgical patients

1 reference

12 December 2020

Tricyclic dose requirements across pregnancy

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12 December 2020

Effect of age and gender on tirilazad pharmacokinetics in humans

1 reference

12 December 2020

Age- and gender-related differences in diazepam pharmacokinetics.

1 reference

12 December 2020

Absorption and disposition of ibuprofen in the elderly

1 reference

12 December 2020

Disposition of alprazolam in human volunteers. Differences between genders

1 reference

12 December 2020

Route of administration and sex differences in the pharmacokinetics of aspirin, administered as its lysine salt

1 reference

12 December 2020

1 reference

12 December 2020

Factors Influencing the Pharmacokinetics of Cyclosporine in Man

1 reference

12 December 2020

The pharmacokinetic profile of nimesulide in healthy volunteers

1 reference

12 December 2020

Influence of sex, menstrual cycle and oral contraception on the disposition of nitrazepam

1 reference

12 December 2020

Influence of age, gender, and obesity on salicylate kinetics following single doses of aspirin

1 reference

12 December 2020

Salicylate metabolism: effects of age and sex in adults

1 reference

12 December 2020

Estrogen preserves a normal intestinal responsiveness to 1,25-dihydroxyvitamin D3 in oophorectomized women.

1 reference

12 December 2020

Gender and oral contraceptive steroids as determinants of drug glucuronidation: effects on clofibric acid elimination

1 reference

12 December 2020

The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites

1 reference

12 December 2020

Diazepam disposition determinants

1 reference

12 December 2020

Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance

1 reference

12 December 2020

Desmethyldiazepam kinetics in the elderly after oral prazepam

1 reference

12 December 2020

Metabolism of digoxin, digoxigenin digitoxosides and digoxigenin in human hepatocytes and liver microsomes

1 reference

12 December 2020

1 reference

12 December 2020

First-pass metabolism of cyclosporin by the gut

1 reference

12 December 2020

Pregnancy and epilepsy

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12 December 2020

The disposition of caffeine during and after pregnancy

1 reference

12 December 2020

Potentiation of the biologic effect of administered cortisol by estrogen treatment

1 reference

12 December 2020

Gender differences in hepatic induction and inhibition of theophylline pharmacokinetics and metabolism

1 reference

12 December 2020

Biologic determinants of propranolol disposition: results from 1308 patients in the Beta-Blocker Heart Attack Trial

1 reference

12 December 2020

Acetaminophen kinetics in the elderly

1 reference

12 December 2020

Does the time of the month affect the function of the gut?

1 reference

12 December 2020

Genetic polymorphism of S-mephenytoin hydroxylation

1 reference

12 December 2020

Sex differences in bipolar affective disorder: neuroleptic dosage variance

1 reference

12 December 2020

Effect of subject age and gender on the pharmacokinetics of oral triazolam and temazepam

1 reference

12 December 2020

Disposition of chlordiazepoxide: Sex differences and effects of oral contraceptives

1 reference

12 December 2020

Alprazolam kinetics in the elderly. Relation to antipyrine disposition

1 reference

12 December 2020

Influence of the menstrual cycle on theophylline pharmacokinetics in asthmatics

1 reference

12 December 2020

Noninvasive tests of CYP3A enzymes

1 reference

12 December 2020

Age and gender effects on chlordiazepoxide kinetics: relation to antipyrine disposition

1 reference

12 December 2020

Drug therapy during pregnancy and lactation.

1 reference

12 December 2020

Inter- and intra-individual variation in the metabolism of methaqualone in man after a single oral dose

1 reference

12 December 2020

Women in clinical drug trials. An update

1 reference

12 December 2020

Hepatic cytochrome P-4503A (CYP3A) activity in the elderly

1 reference

12 December 2020

Single-dose kinetics of clomipramine: relationship to the sparteine and S-mephenytoin oxidation polymorphisms

1 reference

12 December 2020

Demographic factors affecting the pharmacokinetics of cyclosporine estimated by radioimmunoassay

1 reference

12 December 2020

Serum phenytoin, phenobarbital, carbamazepine, albumin; and plasma estradiol, progesterone concentrations during the menstrual cycle in women with epilepsy

1 reference

12 December 2020

Imipramine serum protein binding in healthy subjects

1 reference

12 December 2020

Underrepresentation of women in clinical drug trials

1 reference

12 December 2020

The effect of antibiotics on the efficacy of oral contraceptives. A controversy revisited

1 reference

12 December 2020

Clomipramine metabolism. Model-based analysis of variability factors from drug monitoring data

1 reference

12 December 2020

Steady-state plasma levels of clomipramine and its metabolites: impact of the sparteine/debrisoquine oxidation polymorphism. Danish University Antidepressant Group

1 reference

12 December 2020

64 Identification and localization of cytochromes P450 in gut

1 reference

12 December 2020

Effect of Age and Sex on Human Drug Metabolism

1 reference

12 December 2020

Enhancement of the anti-inflammatory action of hydrocortisone by estrogen

1 reference

12 December 2020

Gender differences in pharmacokinetics and pharmacodynamics of psychotropics: focus on women

1 reference

12 December 2020

1 reference

12 December 2020

The influence of age and gender on the stereoselective metabolism and pharmacokinetics of mephobarbital in humans

1 reference

12 December 2020

Menopause: pharmacodynamics and pharmacokinetics

1 reference

12 December 2020

Effects of age and sex on piroxicam disposition

1 reference

12 December 2020

The interaction of phenytoin and carbamazepine with combined oral contraceptive steroids

1 reference

12 December 2020

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12 December 2020

10.2165/00003495-199550020-00003

Identifiers

DOI

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30 July 2022

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1027353958

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Fatcat ID

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Fatcat

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30 July 2022

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https://api.fatcat.wiki/v0/release/ludtufiw6bhynm7whnhw6uj5gi

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30 July 2022