(Q40970549)

25 September 2017

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title

Hereditary cancer: two hits revisited (English)

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25 September 2017

A G Knudson

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25 September 2017

publication date

1 January 1996

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Journal of Cancer Research and Clinical Oncology

25 September 2017

published in

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25 September 2017

volume

122

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25 September 2017

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25 September 2017

page(s)

135-140

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

25 September 2017

cites work

1 reference

12 December 2020

Loss of a Harvey ras allele in sporadic Wilms' tumour

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12 December 2020

p53 functions as a cell cycle control protein in osteosarcomas

1 reference

12 December 2020

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1 reference

12 December 2020

Human retinoblastoma susceptibility gene: cloning, identification, and sequence

1 reference

12 December 2020

Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14

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12 December 2020

Chromosomal deletion and retinoblastoma

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12 December 2020

Sporadic bilateral retinoblastoma and 13q- chromosomal deletion

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12 December 2020

The approaching era of the tumor suppressor genes

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12 December 2020

Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour

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12 December 2020

Interstitial deletion of short arm of chromosome 11 limited to Wilms' tumor cells in a patient without aniridia

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12 December 2020

Development of homozygosity for chromosome 11p markers in Wilms' tumour

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12 December 2020

Structural evidence for the authenticity of the human retinoblastoma gene

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12 December 2020

Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma

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12 December 2020

Model for the incidence of embryonal cancers: application to retinoblastoma

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12 December 2020

Heredity and cancer in man.

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12 December 2020

Adenomatous polyposis coli gene mutations in ulcerative colitis-associated dysplasias and cancers versus sporadic colon neoplasms.

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12 December 2020

Retinoblastoma A Model of Hereditary Fragile Chromosomal Regions

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12 December 2020

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

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12 December 2020

Computer-assisted analysis of chromosomal abnormalities: detection of a deletion in aniridia-Wilms' tumor syndrome

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12 December 2020

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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12 December 2020

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

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12 December 2020

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

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12 December 2020

Identification of a chromosome 18q gene that is altered in colorectal cancers

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12 December 2020

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer

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12 December 2020

Mutation and cancer: neuroblastoma and pheochromocytoma

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12 December 2020

Familial Breast Cancer, Soft-Tissue Sarcomas, and Other Neoplasms

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12 December 2020

Identification and characterization of the familial adenomatous polyposis coli gene

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12 December 2020

T antigen is bound to a host protein in SY40-transformed cells

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12 December 2020

Ulcerative colitis and colorectal cancer. A population-based study

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12 December 2020

The APC gene product in normal and tumor cells

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12 December 2020

Genetic changes of both p53 alleles associated with the conversion from colorectal adenoma to early carcinoma in familial adenomatous polyposis and non-familial adenomatous polyposis patients

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12 December 2020

p53 protein expression in ulcerative colitis-associated colorectal dysplasia and carcinoma

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12 December 2020

Mutation of a mutL homolog in hereditary colon cancer

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12 December 2020

Chromosomal imbalance in the Aniridia-Wilms' tumor association: 11p interstitial deletion

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12 December 2020

Retinoblastoma: a prototypic hereditary neoplasm

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12 December 2020

Stem cell regulation, tissue ontogeny, and oncogenic events

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12 December 2020

A genetic model for colorectal tumorigenesis

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12 December 2020

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

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12 December 2020

Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC.

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12 December 2020

Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

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12 December 2020

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

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12 December 2020

Mutation and cancer: statistical study of retinoblastoma

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12 December 2020

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

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12 December 2020

Second primary neoplasms in patients with retinoblastoma

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12 December 2020

Hereditary cancer, oncogenes, and antioncogenes.

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12 December 2020

A general theory of carcinogenesis

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12 December 2020

Aniridia-Wilms’ tumor association: evidence for specific deletion of 11p13

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12 December 2020

Rearrangement of the p53 gene in human osteogenic sarcomas

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12 December 2020

Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer

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12 December 2020

Patient with 13 Chromosome Deletion: Evidence That the Retinoblastoma Gene Is a Recessive Cancer Gene

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12 December 2020

Mutation and cancer: a model for Wilms' tumor of the kidney

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12 December 2020

Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours.

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12 December 2020

Specific chromosome defect associated with human small-cell lung cancer; deletion 3p(14-23)

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12 December 2020

Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D

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12 December 2020

Antioncogenes and human cancer

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12 December 2020

Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP).

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12 December 2020

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

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12 December 2020

Identifiers

DOI

10.1007/BF01366952

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25 September 2017

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