(Q40801530)

23 September 2017

title

A novel cellular phenotype for familial hypercholesterolemia due to a defect in polarized targeting of LDL receptor (English)

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familial hypercholesterolemia

23 September 2017

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U M Koivisto

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23 September 2017

A L Hubbard

series ordinal

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23 September 2017

I Mellman

series ordinal

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23 September 2017

language of work or name

English

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publication date

1 June 2001

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23 September 2017

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23 September 2017

volume

105

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23 September 2017

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23 September 2017

page(s)

575-585

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Microvillus inclusion disease: a genetic defect affecting apical membrane protein traffic in intestinal epithelium

23 September 2017

cites work

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7 January 2021

Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes

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7 January 2021

Biogenesis of the rat hepatocyte plasma membrane in vivo: comparison of the pathways taken by apical and basolateral proteins using subcellular fractionation

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7 January 2021

Molecular bases for the recognition of tyrosine-based sorting signals

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7 January 2021

Compromised cytoarchitecture and polarized trafficking in autosomal dominant polycystic kidney disease cells

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7 January 2021

The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors

1 reference

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7 January 2021

TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking

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7 January 2021

Origins of cell polarity

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7 January 2021

A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells

1 reference

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7 January 2021

Distribution and function of AP-1 clathrin adaptor complexes in polarized epithelial cells

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7 January 2021

A simplified system for generating recombinant adenoviruses

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7 January 2021

Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice

1 reference

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7 January 2021

Molecular genetics of the LDL receptor gene in familial hypercholesterolemia

1 reference

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7 January 2021

Use of monoclonal anti-receptor antibodies to probe the expression of the low density lipoprotein receptor in tissues of normal and Watanabe heritable hyperlipidemic rabbits

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7 January 2021

Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant

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7 January 2021

WIF-B cells: an in vitro model for studies of hepatocyte polarity

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7 January 2021

Apical plasma membrane proteins and endolyn-78 travel through a subapical compartment in polarized WIF-B hepatocytes.

1 reference

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7 January 2021

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

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7 January 2021

Newly synthesized canalicular ABC transporters are directly targeted from the Golgi to the hepatocyte apical domain in rat liver

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7 January 2021

Membrane protein trafficking through the common apical endosome compartment of polarized Caco-2 cells.

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7 January 2021

Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells

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7 January 2021

Saturation of, and competition for entry into, the apical secretory pathway

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7 January 2021

Mechanisms of cell polarity: sorting and transport in epithelial cells

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7 January 2021

Basolateral sorting of LDL receptor in MDCK cells: the cytoplasmic domain contains two tyrosine-dependent targeting determinants

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7 January 2021

Common signals control low density lipoprotein receptor sorting in endosomes and the Golgi complex of MDCK cells

1 reference

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7 January 2021

Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells.

1 reference

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7 January 2021

Transepithelial transport of immunoglobulins

1 reference

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7 January 2021

Plasma membrane protein sorting in polarized epithelial cells

1 reference

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7 January 2021

A PDZ-interacting domain in CFTR is an apical membrane polarization signal

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7 January 2021

Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells

1 reference

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7 January 2021

A mouse model of human familial hypercholesterolemia: markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet.

1 reference

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7 January 2021

The receptor recycling pathway contains two distinct populations of early endosomes with different sorting functions

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900371-3

7 January 2021

Evidence for apical endocytosis in polarized hepatic cells: phosphoinositide 3-kinase inhibitors lead to the lysosomal accumulation of resident apical plasma membrane proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900371-3

7 January 2021

PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900371-3

7 January 2021

Cytoplasmic sequence required for basolateral targeting of LDL receptor in livers of transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900371-3

7 January 2021

Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900371-3

7 January 2021

10.1016/S0092-8674(01)00371-3

Identifiers

DOI

1 reference

23 September 2017

1 reference