(Q40887257)

24 September 2017

title

Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway (English)

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24 September 2017

C M Leu

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24 September 2017

C Chang

series ordinal

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24 September 2017

C Hu

series ordinal

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24 September 2017

language of work or name

English

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publication date

1 March 2000

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24 September 2017

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24 September 2017

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24 September 2017

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24 September 2017

page(s)

1665-1675

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The Bcl-2 protein family: arbiters of cell survival

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

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Reversal of EBV Immortalization Precedes Apoptosis in IL-6–Induced Human B Cell Terminal Differentiation

21 January 2018

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Inhibition of Bax channel-forming activity by Bcl-2

21 January 2018

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Regulation of surface-differentiation molecules by epidermal growth factor, transforming growth factor alpha, and hydrocortisone in human mammary epithelial cells transformed by an activated c-Ha-ras proto-oncogene

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

21 January 2018

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Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

21 January 2018

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

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A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum

21 January 2018

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Multiple pathways are involved in protection of MCF-7 cells against death due to protein synthesis inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

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Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I.

21 January 2018

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Platelet-derived growth factor is an autocrine stimulator for the growth and survival of human esophageal carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Amplification of the EGF receptor and c-myc genes in human esophageal cancers

21 January 2018

1 reference

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p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of EGF and insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

21 January 2018

1 reference

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Activation of overexpressed receptors for insulin and epidermal growth factor interferes in mitogenic signaling without affecting the activation of p21ras

21 January 2018

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High incidence of EGF receptor hyperproduction in esophageal squamous-cell carcinomas

21 January 2018

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Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

BCL-2 and MCL-1 expression in Chinese hamster ovary cells inhibits intracellular acidification and apoptosis induced by staurosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

21 January 2018

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Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Channel formation by antiapoptotic protein Bcl-2.

21 January 2018

1 reference

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21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

CD28 can promote T cell survival through a phosphatidylinositol 3-kinase-independent mechanism

21 January 2018

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Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

Signal transduction pathways that regulate cell survival and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

7 January 2021

Epidermal growth factor, but not hepatocyte growth factor, suppresses the apoptosis induced by transforming growth factor-beta in fetal hepatocytes in primary culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

7 January 2021

Prognostic significance of transforming growth factor-alpha in human esophageal carcinoma. Implication for the autocrine proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

7 January 2021

Staurosporine, a Potentially Important Gift from a Microorganism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

7 January 2021

Prognostic significance of epidermal growth factor receptor in esophageal squamous cell carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

7 January 2021

Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

7 January 2021

7-Hydroxystaurosporine (UCN-01) Induces Apoptosis in Human Colon Carcinoma and Leukemia Cells Independently of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

7 January 2021

Type I insulin-like growth factor receptor activation regulates apoptotic proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

7 January 2021

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203452

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203452

1 reference

Dimensions Publication ID

24 September 2017

1042793305

0 references

1 reference