(Q40875533)

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Preclinical evaluation of drug-drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction.

scientific article published in November 1997

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9402946%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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Europe PubMed Central

Preclinical evaluation of drug-drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9402946%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

drug interaction

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1

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8 November 2019

author name string

P Maurel

2

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8 November 2019

M J Gomez-Lechon

3

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8 November 2019

L C Cheng

4

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8 November 2019

M Jurima-Romet

5

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8 November 2019

publication date

1 November 1997

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8 November 2019

Chemico-biological Interactions

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8 November 2019

107

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8 November 2019

1-2

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8 November 2019

5-16

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8 November 2019

Substrates of human hepatic cytochrome P450 3A4.

1 reference

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7 January 2021

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

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7 January 2021

Multiple drug interactions with cyclosporine in a heart transplant patient

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7 January 2021

Evaluation of cyclosporin-phenytoin interaction with observations on cyclosporin metabolites

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Induction and autoinduction properties of rifamycin derivatives: a review of animal and human studies

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7 January 2021

33 Induction protocols for cytochromes P450IIIA in Vivo and in primary cultures of animal and human hepatocytes

1 reference

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7 January 2021

Omeprazole, an inducer of human CYP1A1 and 1A2, is not a ligand for the Ah receptor

1 reference

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7 January 2021

Use of human hepatocytes to study P450 gene induction

1 reference

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7 January 2021

Preparation of human hepatocytes for primary culture

1 reference

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7 January 2021

Optimization of cryopreservation procedures for rat and human hepatocytes

1 reference

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7 January 2021

Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450.

1 reference

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7 January 2021

Culture of human hepatocytes from small surgical liver biopsies. Biochemical characterization and comparison with in vivo

1 reference

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7 January 2021

High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

1 reference

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7 January 2021

Chapter 4 Preparation of Isolated Rat Liver Cells

1 reference

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7 January 2021

Comparative effects of omeprazole on xenobiotic metabolizing enzymes in the rat and human

1 reference

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7 January 2021

Polybrominated biphenyl induction of cytochrome P450 mixed function oxidase activity in primary rat and human hepatocytes.

1 reference

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7 January 2021

Induction of CYP1A and glutathione S-transferase activities by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human hepatocyte cultures.

1 reference

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7 January 2021

Purification of two cytochrome P450 isozymes related to CYP2A and CYP3A gene families from monkey (baboon, Papio papio) liver microsomes. Cross reactivity with human forms

1 reference

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7 January 2021

Expression of cytochrome P-450 enzymes in cultured human hepatocytes

1 reference

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7 January 2021

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

1 reference

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7 January 2021

Mixed function oxidase and UDP-glucuronyltransferase activities in the human Hep G2 hepatoma cell line

1 reference

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7 January 2021

HepG2 cells: an in vitro model for P450-dependent metabolism of acetaminophen

1 reference

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7 January 2021

Pharmacokinetic variability of zidovudine in HIV-infected individuals: subgroup analysis and drug interactions

1 reference

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7 January 2021

Effect of xenobiotics on monooxygenase activities in cultured human hepatocytes

1 reference

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7 January 2021

Ethanol and isopentanol increase CYP3A and CYP2E in primary cultures of human hepatocytes

1 reference

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7 January 2021

Metabolism of the new immunosuppressor cyclosporin G by human liver cytochromes P450

1 reference

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7 January 2021

Induction of cytochrome P450 3A by metyrapone in human hepatocyte culture

1 reference

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7 January 2021

Identifiers

10.1016/S0009-2797(97)00070-7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9402946%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9402946%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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