(Q408572)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q99720

auxiliary protein involved in transmembrane transport

1 reference

Transporter Classification Database ID

8.A.63.1.1

hierarchical database ID heuristic

2 October 2019

based on heuristic

1 reference

13 November 2019

1 reference

13 November 2019

G protein-coupled opioid receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

identical protein binding

1 reference

24 April 2018

Crystal structure of the human σ1 receptor

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99720&geneProductId=UniProtKB:Q99720

signaling receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

cell component

postsynaptic membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

endoplasmic reticulum membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

growth cone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

lipid droplet

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

integral component of plasma membrane

TAS

1 reference

8 April 2019

Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

TAS

cell junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

nuclear inner membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

nuclear outer membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

nuclear envelope

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

3 references

8 April 2019

8 April 2019

Colocalization of sterol isomerase and sigma(1) receptor at endoplasmic reticulum and nuclear envelope level

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

8 April 2019

Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

integral component of membrane

Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

8 April 2019

8 April 2019

Crystal structure of the human σ1 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

cytoplasmic vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

postsynaptic density

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

8 April 2019

Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

3 references

8 April 2019

8 April 2019

Colocalization of sterol isomerase and sigma(1) receptor at endoplasmic reticulum and nuclear envelope level

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

IBA

biological process

lipid transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

1 reference

8 April 2019

regulation of neuron apoptotic process

IMP

1 reference

8 April 2019

A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

nervous system development

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

G protein-coupled opioid receptor signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

protein homotrimerization

1 reference

8 April 2019

Crystal structure of the human σ1 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99720

signal transduction

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99720&geneProductId=UniProtKB:Q99720

physically interacts with

1 reference

6953

17 August 2016

1 reference

6678

17 August 2016

1 reference

6680

17 August 2016

1 reference

1606

English

17 August 2016

Viroporin 3a

Affinity Capture-MS

1 reference

https://thebiogrid.org/news/227

19 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

BioGRID

pentoxyverine

object of statement has role

agonist

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL73234

exact match

http://purl.uniprot.org/uniprot/Q99720

1 reference

D12.776.543.750.695.620.775.500

Identifiers.org

Identifiers

MeSH descriptor ID

D000097605

subject named as

Sigma-1 Receptor

0 references

MeSH tree code

0 references

D12.776.543.750.720.600.610.775.500

0 references

D12.776.543.750.750.555.610.775.500

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

4 August 2016

1 reference

4 August 2016

Transporter Classification Database ID

0 references

0 references

0 references

8.A.63.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database