(Q40726564)

23 September 2017

title

Design of peptide-based inhibitors of human islet amyloid polypeptide fibrillogenesis (English)

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23 September 2017

Louise A Scrocchi

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23 September 2017

Yan Chen

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23 September 2017

Stefko Waschuk

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23 September 2017

Feng Wang

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23 September 2017

Sindy Cheung

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23 September 2017

Audrey A Darabie

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23 September 2017

JoAnne McLaurin

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23 September 2017

Paul E Fraser

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23 September 2017

language of work or name

English

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publication date

1 May 2002

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Journal of Molecular Biology

23 September 2017

published in

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23 September 2017

volume

318

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23 September 2017

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23 September 2017

page(s)

697-706

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On the Relation of Chronic Interstitial Pancreatitis to the Islands of Langerhans and to Diabetes Melutus

23 September 2017

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Islet amyloid polypeptide (IAPP;Amylin) influences the endocrine but not the exocrine rat pancreas

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Inhibitory action of islet amyloid polypeptide and calcitonin gene-related peptide on release of insulin from the isolated perfused rat pancreas

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Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

7 January 2021

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Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro.

7 January 2021

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Islet amyloid, islet-amyloid polypeptide, and diabetes mellitus

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Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein

7 January 2021

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Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

7 January 2021

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Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin

7 January 2021

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Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Different sensitivity to the cytotoxic action of IAPP fibrils in two insulin-producing cell lines, HIT-T15 and RINm5F cells

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B Cell Granule Peptides Affect Human Islet Amyloid Polypeptide (IAPP) Fibril Formationin Vitro

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Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model

7 January 2021

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Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro

7 January 2021

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The relation of islet amyloid to the clinical type of diabetes

7 January 2021

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Longitudinal studies on the development of diabetes in individual Macaca nigra

7 January 2021

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A feline model of experimentally induced islet amyloidosis

7 January 2021

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7 January 2021

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Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties

7 January 2021

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Identification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implications for islet amyloid formation

7 January 2021

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7 January 2021

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Changes in amylin and amylin-like peptide concentrations and beta-cell function in response to sulfonylurea or insulin therapy in NIDDM.

7 January 2021

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Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet beta-cells.

7 January 2021

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Preparation of synthetic human islet amyloid polypeptide (IAPP) in a stable conformation to enable study of conversion to amyloid-like fibrils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900164-X

10.1016/S0022-2836(02)00164-X

7 January 2021

Identifiers

DOI

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23 September 2017

1 reference