(Q40783010)

23 September 2017

title

Wildtype Kras2 can inhibit lung carcinogenesis in mice (English)

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23 September 2017

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Z Zhang

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23 September 2017

Y Wang

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23 September 2017

H G Vikis

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23 September 2017

L Johnson

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23 September 2017

G Liu

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23 September 2017

J Li

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23 September 2017

M W Anderson

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23 September 2017

R C Sills

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23 September 2017

H L Hong

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23 September 2017

T R Devereux

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23 September 2017

T Jacks

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23 September 2017

K L Guan

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23 September 2017

M You

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23 September 2017

language of work or name

English

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publication date

1 September 2001

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23 September 2017

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23 September 2017

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23 September 2017

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23 September 2017

page(s)

25-33

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Role of proto-oncogene activation in carcinogenesis

23 September 2017

cites work

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7 January 2021

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7 January 2021

How does p21ras transform cells?

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7 January 2021

Dominant transformation by mutated human ras genes in vitro requires more than 100 times higher expression than is observed in cancers

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7 January 2021

Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse

1 reference

7 January 2021

A molecular approach to leukemogenesis: mouse lymphomas contain an activated c-ras oncogene

1 reference

7 January 2021

Malignant transformation of early passage rodent cells by a single mutated human oncogene

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7 January 2021

A point mutation in the last intron responsible for increased expression and transforming activity of the c-Ha-ras oncogene

1 reference

7 January 2021

Predisposition to neoplastic transformation caused by gene replacement of H-ras1.

1 reference

7 January 2021

Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7.

1 reference

7 January 2021

The dominant negative Ras mutant, N17Ras, can inhibit signaling independently of blocking Ras activation

1 reference

7 January 2021

Suppression of pancreatic cancer by the dominant negative ras mutant, N116Y.

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7 January 2021

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

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7 January 2021

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

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7 January 2021

Lung Tumors in Mice: Application to Carcinogenesis Bioassay

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7 January 2021

Inactivation of both Rb and p53 pathways in mouse lung epithelial cell lines

1 reference

7 January 2021

High frequency of codon 61 K-ras A-->T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene

1 reference

7 January 2021

Function and regulation of ras.

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7 January 2021

Activators and effectors of ras p21 proteins

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7 January 2021

Prognostic value of loss of heterozygosity and KRAS2 mutations in lung adenocarcinoma.

1 reference

7 January 2021

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

7 January 2021

ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons

1 reference

7 January 2021

Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons

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7 January 2021

Neurotrophin signalling

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7 January 2021

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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7 January 2021

Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

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7 January 2021

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1 reference

7 January 2021

Activated N-ras gene induces neuronal differentiation of PC12 rat pheochromocytoma cells.

1 reference

7 January 2021

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

1 reference

7 January 2021

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

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7 January 2021

ras gene Amplification and malignant transformation

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7 January 2021

The second intron of the K-ras gene contains regulatory elements associated with mouse lung tumor susceptibility

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7 January 2021

A cellular oncogene (c-Ki-ras) is amplified, overexpressed and located within karyotypic abnormalities in mouse adrenocortical tumour cells

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7 January 2021

c-Ki-ras amplification in human lung cancer

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7 January 2021

Cellular protoonocogenes are infrequently amplified in untreated non-small cell lung cancer

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7 January 2021

The clinicopathological significance of K-RAS point mutation and gene amplification in endometrial cancer

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7 January 2021

Oncogene amplification in squamous cell carcinoma of the oral cavity.

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7 January 2021

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

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7 January 2021

Identifiers

DOI

10.1038/NG721

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Dimensions Publication ID

23 September 2017

1014242812

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