(Q40760800)

23 September 2017

title

MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c release (English)

1 reference

23 September 2017

Erika M Gibson

1 reference

23 September 2017

Elizabeth S Henson

series ordinal

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23 September 2017

Jacylyn Villanueva

series ordinal

1 reference

23 September 2017

Spencer B Gibson

series ordinal

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23 September 2017

language of work or name

English

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publication date

26 December 2001

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Journal of Biological Chemistry

23 September 2017

published in

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23 September 2017

volume

277

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23 September 2017

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23 September 2017

page(s)

10573-10580

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Role of redox potential and reactive oxygen species in stress signaling

23 September 2017

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1 reference

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Mitochondria and apoptosis

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Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

21 January 2018

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MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis

21 January 2018

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Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents

21 January 2018

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Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL

21 January 2018

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Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.

21 January 2018

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Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event

21 January 2018

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The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ

21 January 2018

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Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator

21 January 2018

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Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts

21 January 2018

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Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter

21 January 2018

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HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation

21 January 2018

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Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1

21 January 2018

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MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

21 January 2018

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Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death

21 January 2018

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MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton

21 January 2018

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NF-kappa B-mediated chemoresistance in breast cancer cells

21 January 2018

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Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

21 January 2018

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Death receptors: signaling and modulation

21 January 2018

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Cisplatin induces the proapoptotic conformation of Bak in a deltaMEKK1-dependent manner

21 January 2018

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The C. elegans orthologue ceBNIP3 interacts with CED-9 and CED-3 but kills through a BH3- and caspase-independent mechanism

21 January 2018

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BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore

21 January 2018

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Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

21 January 2018

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Novel role for JNK as a stress-activated Bcl2 kinase

21 January 2018

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BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

21 January 2018

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Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M108366200

1 reference

23 September 2017

1 reference