(Q40623783)

22 September 2017

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title

The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis (English)

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22 September 2017

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Omura S

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22 September 2017

language of work or name

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1 September 1976

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22 September 2017

Bacteriological Reviews

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22 September 2017

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22 September 2017

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22 September 2017

681-697

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Induction of Staphylococcus aureus Lactose Permease in the Absence of Glycerolipid Synthesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

EFFECT OF TEMPERATURE ON THE COMPOSITION OF FATTY ACIDS IN ESCHERICHIA COLI

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Acetate Utilization and Macromolecular Synthesis During Sporulation of Yeast

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

A Saccharomyces cerevisiae mutant defective in saturated fatty acid biosynthesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Fatty acid mutant of E. coli lacking a beta-hydroxydecanoyl thioester dehydrase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

On the enzymatic synthesis of unsaturated fatty acids in Escherichia coli

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Regulation of the fatty acid composition of the membrane phospholipids of Escherichia coli

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Inhibition of Lipid Synthesis in Escherichia coli Cells by the Antibiotic Cerulenin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Regulation of Phospholipid Synthesis in Escherichia coli by Guanosine Tetraphosphate

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Lipid Synthesis During Sporulation of Saccharomyces cerevisiae

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Changes in the lipid composition and fine structure of Saccharomyces cerevisiae during ascus formation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Chapter 2 Regulation of Sporulation in Yeast

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Temperature-Sensitive Mutants of Escherichia coli Requiring Saturated and Unsaturated Fatty Acids for Growth: Isolation and Properties

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Metabolism and function of the membrane phospholipids of Escherichia coli

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Induction of citrate transport in Bacillus subtilis during the absence of phospholipid synthesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Temperature control of phospholipid biosynthesis in Escherichia coli

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Physical properties of membrane lipids: biological relevance and regulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Biogenesis of membrane lipids: mutants of Escherichia coli with temperature-sensitive phosphatidylserine decarboxylase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Insertion of a minor protein into the outer membrane of Escherichia coli during inhibition of lipid synthesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Inhibition of de novo fatty acid synthesis by the antibiotic cerulenin in Bacillus subtilis: effects on citrate-Mg2+ transport and synthesis of macromolecules

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Inhibition of sporulation by cerulenin and its reversion by exogenous fatty acids in Saccharomyces cerevisiae

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Enzymic Synthesis of an Aromatic Ring from Acetate Units. Partial Purification and Some Properties of Flavanone Synthase from Cell-Suspension Cultures of Petroselinum hortense

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Evidence that acyl coenzyme A synthetase activity is required for repression of yeast acetyl coenzyme A carboxylase by exogenous fatty acids

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Relationship between the structures of fatty acid amide derivatives and their antimicrobial activities

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Antigen specific for bacteria resistant to tetracycline

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Thermal regulation of the membrane lipid composition of Escherichia coli. Evidence for the direct control of fatty acid synthesis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Studies on cerulenin, 3. Isolation and physico-chemical properties of cerulenin

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Acyl carrier protein. XV. Studies of -ketoacyl-acyl carrier protein synthetase.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

The antibacterial activity of 3-decynoyl-n-acetylcysteamine. Inhibition in vivo of beta-hydroxydecanoyl thioester dehydrase

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Acyl carrier protein. 13. Beta-ketoacyl acyl carrier protein synthetase from Escherichia coli

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Inhibition of the biosynthesis of leucomycin, a macrolide antibiotic, by cerulenin

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Target of inhibition by the anti-lipogenic antibiotic cerulenin of sterol synthesis in yeast

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Detection of an inducible membrane protein associated with R-factor-mediated tetracycline resistance

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Stringent and Relaxed Control of Phospholipid Metabolism in Escherichia coli

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Fat metabolism in higher plants. Properties of the palmityl acyl carrier protein: stearyl acyl carrier protein elongation system in maturing safflower seed extracts.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Preparation of 13C- and 3H-labeled cerulenin and biosynthesis with 13C-NMR

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Biosynthetic studies using carbon-13 enriched precursors on the 16-membered macrolide antibiotic leucomycin A3

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Substitution of cellular fatty acids in yeast cells by the antibiotic cerulenin and exogenous fatty acids

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Production of amphotericin B-14C by Streptomyces nodosus fermentation, and preparation of the amphotericin B-14C-methyl-ester.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Studies on cerulenin. V. Structure of cerulenin

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

Acyl carrier protein. XIV. Further studies on beta-ketoacyl acyl carrier protein synthetase from Escherichia coli.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

RC gene control in Escherichia coli is not restricted to RNA synthesis

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413976

STUDIES ON CERULENIN. IV. BIOLOGICAL CHARACTERISTICS OF CERULENIN

20 August 2018

1 reference

12 December 2020

Studies on Cerulenin. VI. Some Spectroscopic Features of Cerulenin

1 reference

12 December 2020

The biosynthesis of the macrolide antibiotic lucensomycin

1 reference

12 December 2020

The biosynthesis of beta-hydroxy-beta-methylglutaryl coenzyme A in yeast. 3. Purification and properties of the condensing enzyme thiolase system

1 reference

12 December 2020

The structure of cephalonic acid, a pentaprenyl terpenoid

1 reference

12 December 2020

Factors Controlling the Sporulation of Yeasts II. The Sporulation Phase

1 reference

12 December 2020

STUDIES ON CERULENIN. II. BIOLOGICAL ASSAY AND FERMENTATION OF CERULENIN

1 reference

12 December 2020

THE STRUCTURE OF HELVOLIC ACID

1 reference

12 December 2020

Induction of Tetracycline Resistance in Staphylococcus aureus in the Absence of Lipid Synthesis

1 reference

12 December 2020

Inhibition of 6-Methylsalicylic Acid Synthesis by the Antibiotic Cerulenin

1 reference

12 December 2020

Stringent control of fatty acid synthesis in Escherichia coli. Possible regulation of acetyl coenzyme A carboxylase by ppGpp

1 reference

12 December 2020

Fatty acid synthetases from Euglena gracilis

1 reference

12 December 2020

Structure of prumycin

1 reference

12 December 2020

The action mechanism of cerulenin. I. Effect of cerulenin on sterol and fatty acid biosynthesis in yeast

1 reference

12 December 2020

Inhibition of sterol and fatty acid biosyntheses by cerulenin in cell-free systems of yeast

1 reference

12 December 2020

Synthesis of unsaturated fatty acids and the lesion in fab B mutants

1 reference

12 December 2020

Inhibition of fatty acid synthesis by the antibiotic cerulenin. Specific inactivation of beta-ketoacyl-acyl carrier protein synthetase

1 reference

12 December 2020

rel Gene control of lipid synthesis in Escherichia coli. Evidence for eliminating fatty acid synthesis as the sole regulatory site

1 reference

12 December 2020

Inhibition of fatty acid synthetases by the antibiotic cerulenin

1 reference

12 December 2020

Specific inhibition of candicidin biosynthesis by the lipogenic inhibitor cerulenin

1 reference

12 December 2020

Mutants of Escherichia coli with temperature-sensitive malonyl coenzyme A-acyl carrier protein transacylase

1 reference

12 December 2020

Revised structure of cerulenin

1 reference

12 December 2020

Microbiological transformations of fusidane-type antibiotics. A correlation between fusidic acid and helvolic acid

1 reference

12 December 2020

Studies on microbial products. I. Helvolic acid and related compounds. I. 7-desacetoxyhelvolic acid and helvolinic acid

1 reference

12 December 2020

STUDIES ON CERULENIN. I. STUDIES ON CERULENIN PRODUCING STRAIN

1 reference

12 December 2020

Identifiers

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22 September 2017

PubMed publication ID

791237

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