(Q40603129)

22 September 2017

title

Engineered human IgG antibodies with longer serum half-lives in primates (English)

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22 September 2017

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Paul R Hinton

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22 September 2017

Mary G Johlfs

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22 September 2017

Joanna M Xiong

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22 September 2017

Kelly Hanestad

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22 September 2017

Kelly C Ong

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22 September 2017

Chuck Bullock

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22 September 2017

Stephen Keller

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22 September 2017

Meina Tao Tang

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22 September 2017

J Yun Tso

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22 September 2017

Max Vásquez

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22 September 2017

Naoya Tsurushita

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22 September 2017

language of work or name

English

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publication date

29 December 2003

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Journal of Biological Chemistry

22 September 2017

published in

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22 September 2017

volume

279

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22 September 2017

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22 September 2017

page(s)

6213-6216

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Immunotherapy: past, present and future

22 September 2017

cites work

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Natural and designer binding sites made by phage display technology

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Engineered antibodies with increased activity to recruit complement

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High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

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An Fc receptor structurally related to MHC class I antigens

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Multiple roles for the major histocompatibility complex class I- related receptor FcRn

21 January 2018

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The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor

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Increasing the serum persistence of an IgG fragment by random mutagenesis.

21 January 2018

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Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.

21 January 2018

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Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants.

21 January 2018

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Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site-directed mutagenesis.

21 January 2018

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Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding

21 January 2018

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21 January 2018

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Computational determination of the structure of rat Fc bound to the neonatal Fc receptor.

21 January 2018

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Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution

21 January 2018

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Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,)

21 January 2018

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21 January 2018

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Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

21 January 2018

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Cloning of decay-accelerating factor suggests novel use of splicing to generate two proteins

21 January 2018

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Expression of full-length immunoglobulins in Escherichia coli: rapid and efficient production of aglycosylated antibodies.

21 January 2018

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Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice

21 January 2018

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Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn

21 January 2018

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Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn

21 January 2018

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Molecular dynamics of native protein. I. Computer simulation of trajectories

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.C300470200

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22 September 2017

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