(Q40691219)

English

Electrophilic prostaglandins and lipid aldehydes repress redox-sensitive transcription factors p53 and hypoxia-inducible factor by impairing the selenoprotein thioredoxin reductase

scientific article published on 6 November 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Electrophilic prostaglandins and lipid aldehydes repress redox-sensitive transcription factors p53 and hypoxia-inducible factor by impairing the selenoprotein thioredoxin reductase (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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author name string

Philip J Moos

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Kornelia Edes

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Pamela Cassidy

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Edmond Massuda

4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

F A Fitzpatrick

5

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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publication date

6 November 2002

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Europe PubMed Central

PubMed publication ID

22 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

22 September 2017

278

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Europe PubMed Central

PubMed publication ID

22 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

745-750

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Cyclopentenone prostaglandins of the J series inhibit the ubiquitin isopeptidase activity of the proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Requirement of a reactive alpha, beta-unsaturated carbonyl for inhibition of tumor growth and induction of differentiation by "A" series prostaglandins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Thioredoxin reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Nuclear exclusion of wild-type p53 in immortalized human retinoblastoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Inflammation, carcinogenesis and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Identification of adducts formed by reaction of guanine nucleosides with malondialdehyde and structurally related aldehydes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Unequivocal demonstration that malondialdehyde is a mutagen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Formation of a prostaglandin A2-glutathione conjugate in L1210 mouse leukemia cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Lipid mediator class switching during acute inflammation: signals in resolution.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Novel patterns of p53 abnormality in breast cancer from Taiwan: experience from a low-incidence area

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Cellular accumulation of p53 protein: an independent prognostic factor in stage II breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Keeping an old friend under control: regulation of p53 stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211134200

21 January 2018

Identifiers

10.1074/JBC.M211134200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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